Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0915c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0914c and Rv0915c are separated by 92 nucleotidesRv0915c and Rv0916c are separated by 14 nucleotidesRv0916c and Rv0917 are separated by 443 nucleotides Rv0914c: Rv0914c - Possible lipid carrier protein or keto acyl-CoA thiolase, at 1,018,727 to 1,019,965 Rv0914c Rv0915c: Rv0915c - PPE family protein PPE14, at 1,020,058 to 1,021,329 Rv0915c Rv0916c: Rv0916c - PE family protein PE7, at 1,021,344 to 1,021,643 Rv0916c Rv0917: Rv0917 - Possible glycine betaine transport integral membrane protein BetP, at 1,022,087 to 1,023,868 Rv0917 Position (kb) 1020 1021 1022Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 1019.133 kb on + strand, within Rv0914cat 1019.134 kb on - strand, within Rv0914cat 1019.253 kb on + strand, within Rv0914cat 1019.478 kb on + strand, within Rv0914cat 1019.514 kb on - strand, within Rv0914cat 1019.514 kb on - strand, within Rv0914cat 1019.514 kb on - strand, within Rv0914cat 1019.514 kb on - strand, within Rv0914cat 1019.606 kb on + strand, within Rv0914cat 1019.875 kb on + strandat 1019.966 kb on - strandat 1019.971 kb on + strandat 1019.971 kb on + strandat 1019.977 kb on - strandat 1019.979 kb on + strandat 1019.979 kb on + strandat 1020.059 kb on + strandat 1020.093 kb on + strandat 1020.094 kb on - strandat 1020.103 kb on + strandat 1020.103 kb on + strandat 1020.103 kb on + strandat 1020.103 kb on + strandat 1020.349 kb on + strand, within Rv0915cat 1020.479 kb on + strand, within Rv0915cat 1020.481 kb on + strand, within Rv0915cat 1020.481 kb on + strand, within Rv0915cat 1020.482 kb on - strand, within Rv0915cat 1020.554 kb on + strand, within Rv0915cat 1020.554 kb on + strand, within Rv0915cat 1020.554 kb on + strand, within Rv0915cat 1020.869 kb on + strand, within Rv0915cat 1020.870 kb on - strand, within Rv0915cat 1020.870 kb on - strand, within Rv0915cat 1020.870 kb on - strand, within Rv0915cat 1020.875 kb on + strand, within Rv0915cat 1020.876 kb on - strand, within Rv0915cat 1020.911 kb on + strand, within Rv0915cat 1021.115 kb on + strand, within Rv0915cat 1021.116 kb on - strand, within Rv0915cat 1021.116 kb on - strand, within Rv0915cat 1021.197 kb on - strand, within Rv0915cat 1021.256 kb on - strandat 1021.283 kb on + strandat 1021.284 kb on - strandat 1021.524 kb on + strand, within Rv0916cat 1021.525 kb on - strand, within Rv0916cat 1021.693 kb on - strandat 1021.697 kb on - strandat 1021.733 kb on + strandat 1022.087 kb on - strandat 1022.207 kb on + strandat 1022.276 kb on + strand, within Rv0917at 1022.276 kb on + strand, within Rv0917

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,019,133 + Rv0914c 0.33 +3.7
1,019,134 - Rv0914c 0.33 +0.7
1,019,253 + Rv0914c 0.42 -0.3
1,019,478 + Rv0914c 0.61 -0.1
1,019,514 - Rv0914c 0.64 +1.3
1,019,514 - Rv0914c 0.64 -0.9
1,019,514 - Rv0914c 0.64 +0.1
1,019,514 - Rv0914c 0.64 -0.5
1,019,606 + Rv0914c 0.71 +2.2
1,019,875 + -1.2
1,019,966 - +0.3
1,019,971 + -1.0
1,019,971 + -0.7
1,019,977 - -1.2
1,019,979 + -0.4
1,019,979 + +1.6
1,020,059 + -0.1
1,020,093 + -0.3
1,020,094 - -0.7
1,020,103 + +0.3
1,020,103 + -0.4
1,020,103 + +0.2
1,020,103 + +0.0
1,020,349 + Rv0915c 0.23 -0.5
1,020,479 + Rv0915c 0.33 -1.0
1,020,481 + Rv0915c 0.33 -1.4
1,020,481 + Rv0915c 0.33 -3.1
1,020,482 - Rv0915c 0.33 -0.4
1,020,554 + Rv0915c 0.39 -1.2
1,020,554 + Rv0915c 0.39 -0.7
1,020,554 + Rv0915c 0.39 +0.8
1,020,869 + Rv0915c 0.64 -0.9
1,020,870 - Rv0915c 0.64 -2.8
1,020,870 - Rv0915c 0.64 +0.0
1,020,870 - Rv0915c 0.64 +0.2
1,020,875 + Rv0915c 0.64 -0.6
1,020,876 - Rv0915c 0.64 -0.1
1,020,911 + Rv0915c 0.67 -1.1
1,021,115 + Rv0915c 0.83 -0.1
1,021,116 - Rv0915c 0.83 -0.7
1,021,116 - Rv0915c 0.83 -0.4
1,021,197 - Rv0915c 0.90 +0.5
1,021,256 - -0.3
1,021,283 + -0.0
1,021,284 - -1.1
1,021,524 + Rv0916c 0.60 -0.2
1,021,525 - Rv0916c 0.60 -0.1
1,021,693 - -0.1
1,021,697 - -0.4
1,021,733 + -1.5
1,022,087 - +2.0
1,022,207 + -1.5
1,022,276 + Rv0917 0.11 +0.7
1,022,276 + Rv0917 0.11 -0.3

Or see this region's nucleotide sequence