Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0625c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0622 and Rv0623 are separated by 92 nucleotidesRv0623 and Rv0624 overlap by 1 nucleotidesRv0624 and Rv0625c are separated by 93 nucleotidesRv0625c and Rv0626 are separated by 131 nucleotidesRv0626 and Rv0627 overlap by 4 nucleotidesRv0627 and Rv0628c are separated by 71 nucleotides Rv0622: Rv0622 - Possible membrane protein, at 715,370 to 716,317 Rv0622 Rv0623: Rv0623 - Possible antitoxin VapB30, at 716,410 to 716,664 Rv0623 Rv0624: Rv0624 - Possible toxin VapC30. Contains PIN domain., at 716,664 to 717,059 Rv0624 Rv0625c: Rv0625c - Probable conserved transmembrane protein, at 717,153 to 717,893 Rv0625c Rv0626: Rv0626 - Possible antitoxin VapB5, at 718,025 to 718,285 Rv0626 Rv0627: Rv0627 - Possible toxin VapC5, at 718,282 to 718,689 Rv0627 Rv0628c: Rv0628c - Conserved hypothetical protein, at 718,761 to 719,912 Rv0628c Position (kb) 717 718Strain fitness (log2 ratio) -2 -1 0 1 2at 716.231 kb on + strandat 716.232 kb on - strandat 716.422 kb on - strandat 716.422 kb on - strandat 716.638 kb on + strand, within Rv0623at 716.639 kb on - strandat 716.797 kb on + strand, within Rv0624at 716.798 kb on - strand, within Rv0624at 716.919 kb on + strand, within Rv0624at 716.920 kb on - strand, within Rv0624at 716.952 kb on + strand, within Rv0624at 716.953 kb on - strand, within Rv0624at 716.970 kb on + strand, within Rv0624at 716.971 kb on - strand, within Rv0624at 717.057 kb on + strandat 717.058 kb on - strandat 717.058 kb on - strandat 717.064 kb on + strandat 717.428 kb on - strand, within Rv0625cat 717.428 kb on - strand, within Rv0625cat 717.718 kb on + strand, within Rv0625cat 717.719 kb on - strand, within Rv0625cat 717.719 kb on - strand, within Rv0625cat 717.802 kb on + strand, within Rv0625cat 717.803 kb on - strand, within Rv0625cat 717.803 kb on - strand, within Rv0625cat 717.813 kb on + strand, within Rv0625cat 717.813 kb on + strand, within Rv0625cat 718.001 kb on + strandat 718.020 kb on + strandat 718.054 kb on + strand, within Rv0626

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
remove
716,231 + +0.8
716,232 - -0.5
716,422 - -0.0
716,422 - -0.4
716,638 + Rv0623 0.89 -0.2
716,639 - +0.0
716,797 + Rv0624 0.34 +0.0
716,798 - Rv0624 0.34 -0.3
716,919 + Rv0624 0.64 -0.3
716,920 - Rv0624 0.65 -0.0
716,952 + Rv0624 0.73 +0.2
716,953 - Rv0624 0.73 +0.0
716,970 + Rv0624 0.77 -0.5
716,971 - Rv0624 0.78 -0.2
717,057 + -0.5
717,058 - -0.9
717,058 - +0.8
717,064 + -1.8
717,428 - Rv0625c 0.37 -0.3
717,428 - Rv0625c 0.37 +2.7
717,718 + Rv0625c 0.76 -1.3
717,719 - Rv0625c 0.76 -1.5
717,719 - Rv0625c 0.76 -1.2
717,802 + Rv0625c 0.88 -0.6
717,803 - Rv0625c 0.88 -0.5
717,803 - Rv0625c 0.88 -0.4
717,813 + Rv0625c 0.89 -0.4
717,813 + Rv0625c 0.89 -1.8
718,001 + -1.6
718,020 + -0.4
718,054 + Rv0626 0.11 -0.1

Or see this region's nucleotide sequence