Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0393

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0392c and Rv0393 are separated by 141 nucleotidesRv0393 and Rv0394c are separated by 15 nucleotidesRv0394c and Rv0395 are separated by 98 nucleotides Rv0392c: Rv0392c - Probable membrane NADH dehydrogenase NdhA, at 471,227 to 472,639 Rv0392c Rv0393: Rv0393 - Conserved 13E12 repeat family protein, at 472,781 to 474,106 Rv0393 Rv0394c: Rv0394c - Possible secreted protein, at 474,122 to 474,841 Rv0394c Rv0395: Rv0395 - Hypothetical protein, at 474,940 to 475,344 Rv0395 Position (kb) 472 473 474 475Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2 3at 472.037 kb on - strand, within Rv0392cat 472.474 kb on - strand, within Rv0392cat 472.541 kb on - strandat 472.673 kb on + strandat 472.674 kb on - strandat 472.674 kb on - strandat 472.681 kb on - strandat 472.706 kb on - strandat 472.854 kb on + strandat 472.854 kb on + strandat 472.855 kb on - strandat 472.855 kb on - strandat 472.894 kb on - strandat 472.992 kb on + strand, within Rv0393at 473.103 kb on + strand, within Rv0393at 473.104 kb on - strand, within Rv0393at 473.213 kb on + strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.226 kb on - strand, within Rv0393at 474.225 kb on + strand, within Rv0394cat 474.226 kb on - strand, within Rv0394cat 474.386 kb on - strand, within Rv0394cat 474.476 kb on - strand, within Rv0394cat 474.593 kb on - strand, within Rv0394cat 474.698 kb on + strand, within Rv0394cat 474.841 kb on + strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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472,037 - Rv0392c 0.57 +1.4
472,474 - Rv0392c 0.88 +0.0
472,541 - -0.0
472,673 + -0.7
472,674 - -0.1
472,674 - +0.3
472,681 - -0.5
472,706 - -0.8
472,854 + +0.6
472,854 + -3.9
472,855 - -0.3
472,855 - -0.0
472,894 - +0.4
472,992 + Rv0393 0.16 -0.3
473,103 + Rv0393 0.24 +1.7
473,104 - Rv0393 0.24 -0.1
473,213 + Rv0393 0.33 -1.8
473,214 - Rv0393 0.33 -0.2
473,214 - Rv0393 0.33 +3.6
473,225 + Rv0393 0.33 -0.4
473,225 + Rv0393 0.33 -0.1
473,225 + Rv0393 0.33 +1.4
473,226 - Rv0393 0.34 -0.3
474,225 + Rv0394c 0.14 -0.5
474,226 - Rv0394c 0.14 -0.0
474,386 - Rv0394c 0.37 -0.1
474,476 - Rv0394c 0.49 -0.1
474,593 - Rv0394c 0.65 -0.5
474,698 + Rv0394c 0.80 +1.7
474,841 + -0.2
474,854 - +0.9
474,854 - -0.0
474,854 - +0.8
474,854 - -0.6

Or see this region's nucleotide sequence