Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0091

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0090 and Rv0091 are separated by 433 nucleotidesRv0091 and Rv0092 are separated by 131 nucleotides Rv0090: Rv0090 - Possible membrane protein, at 98,480 to 99,250 Rv0090 Rv0091: Rv0091 - Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase) + S-adenosylhomocysteine nucleosidase (S-adenosyl-L-homocysteine homocysteinylribohydrolase), at 99,684 to 100,451 Rv0091 Rv0092: Rv0092 - Cation transporter P-type ATPase a CtpA, at 100,583 to 102,868 Rv0092 Position (kb) 99 100 101Strain fitness (log2 ratio) -2 -1 0 1 2 3at 98.693 kb on - strand, within Rv0090at 98.819 kb on - strand, within Rv0090at 99.137 kb on + strand, within Rv0090at 99.138 kb on - strand, within Rv0090at 99.188 kb on + strandat 99.940 kb on + strand, within Rv0091at 99.941 kb on - strand, within Rv0091at 99.941 kb on - strand, within Rv0091at 100.021 kb on - strand, within Rv0091at 100.176 kb on + strand, within Rv0091at 100.179 kb on + strand, within Rv0091at 100.179 kb on + strand, within Rv0091at 100.207 kb on - strand, within Rv0091at 100.207 kb on - strand, within Rv0091at 100.505 kb on + strandat 100.517 kb on + strandat 100.518 kb on - strandat 100.629 kb on + strandat 100.805 kb on + strandat 100.983 kb on + strand, within Rv0092at 100.984 kb on - strand, within Rv0092at 101.124 kb on - strand, within Rv0092at 101.124 kb on - strand, within Rv0092at 101.195 kb on - strand, within Rv0092at 101.195 kb on - strand, within Rv0092at 101.319 kb on + strand, within Rv0092at 101.320 kb on - strand, within Rv0092at 101.409 kb on + strand, within Rv0092at 101.409 kb on + strand, within Rv0092at 101.410 kb on - strand, within Rv0092

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
remove
98,693 - Rv0090 0.28 -1.8
98,819 - Rv0090 0.44 -0.4
99,137 + Rv0090 0.85 +0.1
99,138 - Rv0090 0.85 +1.8
99,188 + -0.0
99,940 + Rv0091 0.33 +2.8
99,941 - Rv0091 0.33 -0.2
99,941 - Rv0091 0.33 +0.7
100,021 - Rv0091 0.44 -1.2
100,176 + Rv0091 0.64 +2.5
100,179 + Rv0091 0.64 -0.1
100,179 + Rv0091 0.64 +1.0
100,207 - Rv0091 0.68 +0.8
100,207 - Rv0091 0.68 +1.2
100,505 + -1.1
100,517 + -1.4
100,518 - +0.8
100,629 + -0.6
100,805 + -1.2
100,983 + Rv0092 0.17 -0.7
100,984 - Rv0092 0.18 -1.9
101,124 - Rv0092 0.24 -1.1
101,124 - Rv0092 0.24 -0.5
101,195 - Rv0092 0.27 -0.1
101,195 - Rv0092 0.27 -0.5
101,319 + Rv0092 0.32 -0.4
101,320 - Rv0092 0.32 -1.7
101,409 + Rv0092 0.36 -0.3
101,409 + Rv0092 0.36 +0.8
101,410 - Rv0092 0.36 +1.9

Or see this region's nucleotide sequence