Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2835c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2833c and Rv2834c are separated by 2 nucleotidesRv2834c and Rv2835c overlap by 4 nucleotidesRv2835c and Rv2836c are separated by 86 nucleotides Rv2833c: Rv2833c - Probable Sn-glycerol-3-phosphate-binding lipoprotein UgpB, at 3,139,174 to 3,140,484 Rv2833c Rv2834c: Rv2834c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpE, at 3,140,487 to 3,141,314 Rv2834c Rv2835c: Rv2835c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpA, at 3,141,311 to 3,142,222 Rv2835c Rv2836c: Rv2836c - Possible DNA-damage-inducible protein F DinF, at 3,142,309 to 3,143,628 Rv2836c Position (kb) 3141 3142 3143Strain fitness (log2 ratio) -2 -1 0 1at 3140.693 kb on - strand, within Rv2834cat 3141.146 kb on - strand, within Rv2834cat 3141.193 kb on + strand, within Rv2834cat 3141.193 kb on + strand, within Rv2834cat 3141.435 kb on + strand, within Rv2835cat 3141.435 kb on + strand, within Rv2835cat 3141.436 kb on - strand, within Rv2835cat 3142.023 kb on + strand, within Rv2835cat 3142.128 kb on - strand, within Rv2835cat 3142.233 kb on + strandat 3142.234 kb on - strandat 3143.084 kb on + strand, within Rv2836c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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3,140,693 - Rv2834c 0.25 +0.0
3,141,146 - Rv2834c 0.80 +0.4
3,141,193 + Rv2834c 0.85 -0.5
3,141,193 + Rv2834c 0.85 -0.4
3,141,435 + Rv2835c 0.14 +0.8
3,141,435 + Rv2835c 0.14 -0.2
3,141,436 - Rv2835c 0.14 +0.1
3,142,023 + Rv2835c 0.78 +1.2
3,142,128 - Rv2835c 0.90 -2.4
3,142,233 + -0.3
3,142,234 - -0.3
3,143,084 + Rv2836c 0.59 -2.1

Or see this region's nucleotide sequence