Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3150

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
3,514,494	+		Rv3148	0.87	-0.3
3,514,495	-		Rv3148	0.87	-1.7
3,514,539	-				-0.1
3,514,763	+		Rv3149	0.14	-1.4
3,514,868	-		Rv3149	0.28	+1.1
3,514,948	+		Rv3149	0.38	-0.6
3,514,948	+		Rv3149	0.38	-0.7
3,514,949	-		Rv3149	0.38	-0.6
3,514,957	+		Rv3149	0.40	-0.6
3,514,957	+		Rv3149	0.40	+1.6
3,514,958	-		Rv3149	0.40	-0.7
3,514,958	-		Rv3149	0.40	-0.4
3,515,297	+		Rv3149	0.84	+0.4
3,515,491	-				-1.4
3,515,871	+		Rv3150	0.34	-0.4
3,515,952	+		Rv3150	0.40	-0.9
3,516,168	+		Rv3150	0.57	-0.7
3,516,168	+		Rv3150	0.57	-0.9
3,516,224	+		Rv3150	0.61	-1.7
3,516,453	+		Rv3150	0.78	+1.6
3,516,512	+		Rv3150	0.82	-1.2
3,516,519	+		Rv3150	0.83	+1.6
3,516,520	-		Rv3150	0.83	-0.5
3,517,596	-		Rv3151	0.35	-0.5