Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3085

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
3,450,029	-				-0.9
3,450,029	-				+0.4
3,450,031	+				-0.1
3,450,031	+				+0.3
3,450,319	-		Rv3084	0.35	+0.9
3,450,619	+		Rv3084	0.67	-1.9
3,450,620	-		Rv3084	0.67	-0.4
3,450,620	-		Rv3084	0.67	+0.9
3,450,647	+		Rv3084	0.70	-1.2
3,451,181	+		Rv3085	0.31	-0.8
3,451,203	-		Rv3085	0.34	-1.7
3,451,697	+				-0.6
3,451,697	+				-3.4
3,451,756	+				-0.4
3,451,756	+				-0.1
3,451,881	-				-0.1
3,451,881	-				-0.8
3,451,881	-				-0.5
3,451,881	-				+0.2
3,451,933	-		Rv3086	0.14	+0.0
3,452,066	+		Rv3086	0.26	-0.0
3,452,351	+		Rv3086	0.51	-0.4
3,452,351	+		Rv3086	0.51	-2.4
3,452,407	+		Rv3086	0.57	+0.2
3,452,408	-		Rv3086	0.57	-0.3
3,452,408	-		Rv3086	0.57	+0.2
3,452,408	-		Rv3086	0.57	+0.3
3,452,408	-		Rv3086	0.57	+0.3
3,452,411	+		Rv3086	0.57	-1.5
3,452,412	-		Rv3086	0.57	-0.2
3,452,412	-		Rv3086	0.57	-0.3