Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1973

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
2,216,211	+		Rv1971	0.73	-1.8
2,216,212	-		Rv1971	0.73	-1.9
2,216,304	+		Rv1971	0.80	+0.4
2,216,360	+		Rv1971	0.84	-0.3
2,216,429	-		Rv1971	0.89	-1.1
2,216,448	+				-1.1
2,216,448	+				-1.8
2,216,449	-				+0.9
2,216,469	+				-0.1
2,216,470	-				-1.2
2,216,600	-				+2.1
2,216,842	+		Rv1972	0.43	-0.5
2,216,843	-		Rv1972	0.44	-1.4
2,216,843	-		Rv1972	0.44	-0.9
2,216,843	-		Rv1972	0.44	+0.0
2,216,913	+		Rv1972	0.56	-2.7
2,216,914	-		Rv1972	0.56	+0.5
2,216,953	+		Rv1972	0.63	+1.7
2,216,953	+		Rv1972	0.63	+0.1
2,216,954	-		Rv1972	0.63	-0.1
2,217,332	+		Rv1973	0.35	-0.3
2,217,405	-		Rv1973	0.50	-1.5
2,217,779	+		Rv1974	0.32	-0.4
2,217,842	+		Rv1974	0.48	-0.1
2,217,843	-		Rv1974	0.49	+1.3
2,217,947	+		Rv1974	0.76	+0.8
2,217,947	+		Rv1974	0.76	+1.7
2,217,947	+		Rv1974	0.76	-0.9
2,218,040	-				-1.5
2,218,172	+		Rv1975	0.18	+0.6
2,218,228	-		Rv1975	0.26	+0.0
2,218,404	+		Rv1975	0.53	-0.1
2,218,405	-		Rv1975	0.53	+0.1
2,218,415	+		Rv1975	0.55	+0.4
2,218,415	+		Rv1975	0.55	+0.1
2,218,415	+		Rv1975	0.55	-0.6
2,218,418	+		Rv1975	0.55	+1.7
2,218,418	+		Rv1975	0.55	-1.3
2,218,418	+		Rv1975	0.55	+0.0
2,218,419	-		Rv1975	0.55	-0.7
2,218,564	-		Rv1975	0.77	-1.1
2,218,606	+		Rv1975	0.83	-0.8
2,218,625	+		Rv1975	0.86	+0.8