Experiment: 7H9 with nitrite 1.5 mM; pH 5.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0187 and Rv0188 are separated by 118 nucleotides Rv0188 and Rv0189c are separated by 78 nucleotides Rv0189c and Rv0190 are separated by 147 nucleotides Rv0190 and Rv0191 are separated by 127 nucleotides
Rv0187: Rv0187 - Probable O-methyltransferase, at 218,705 to 219,367
Rv0187
Rv0188: Rv0188 - Probable conserved transmembrane protein, at 219,486 to 219,917
Rv0188
Rv0189c: Rv0189c - Probable dihydroxy-acid dehydratase IlvD (dad), at 219,996 to 221,723
Rv0189c
Rv0190: Rv0190 - Conserved protein, at 221,871 to 222,161
Rv0190
Rv0191: Rv0191 - Probable conserved integral membrane protein, at 222,289 to 223,530
Rv0191
Position (kb) 219
220
221
222 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 219.148 kb on + strand, within Rv0187 at 219.205 kb on + strand, within Rv0187 at 219.206 kb on - strand, within Rv0187 at 219.298 kb on - strand, within Rv0187 at 219.492 kb on - strand at 219.613 kb on - strand, within Rv0188 at 219.860 kb on - strand, within Rv0188 at 219.915 kb on + strand at 219.916 kb on - strand at 221.806 kb on + strand at 221.806 kb on + strand at 221.806 kb on + strand at 221.807 kb on - strand at 221.807 kb on - strand at 221.807 kb on - strand at 221.816 kb on - strand at 221.868 kb on + strand at 221.911 kb on - strand, within Rv0190 at 221.911 kb on - strand, within Rv0190 at 221.979 kb on + strand, within Rv0190 at 221.980 kb on - strand, within Rv0190 at 221.980 kb on - strand, within Rv0190 at 221.980 kb on - strand, within Rv0190 at 222.318 kb on + strand at 222.319 kb on - strand at 222.381 kb on + strand at 222.381 kb on + strand at 222.381 kb on + strand at 222.381 kb on + strand at 222.382 kb on - strand at 222.385 kb on + strand at 222.385 kb on + strand at 222.385 kb on + strand at 222.386 kb on - strand at 222.386 kb on - strand at 222.386 kb on - strand at 222.386 kb on - strand at 222.386 kb on - strand at 222.458 kb on + strand, within Rv0191 at 222.458 kb on + strand, within Rv0191 at 222.458 kb on + strand, within Rv0191 at 222.458 kb on + strand, within Rv0191 at 222.458 kb on + strand, within Rv0191 at 222.459 kb on - strand, within Rv0191 at 222.459 kb on - strand, within Rv0191 at 222.481 kb on + strand, within Rv0191 at 222.482 kb on - strand, within Rv0191
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with nitrite 1.5 mM; pH 5.5 remove 219,148 + Rv0187 0.67 -0.4 219,205 + Rv0187 0.75 +1.0 219,206 - Rv0187 0.76 -2.0 219,298 - Rv0187 0.89 -0.3 219,492 - -1.9 219,613 - Rv0188 0.29 +1.7 219,860 - Rv0188 0.87 -0.5 219,915 + +0.4 219,916 - -0.3 221,806 + -0.4 221,806 + -0.2 221,806 + -1.0 221,807 - +0.2 221,807 - -0.1 221,807 - -0.7 221,816 - -0.9 221,868 + -0.7 221,911 - Rv0190 0.14 -0.8 221,911 - Rv0190 0.14 -0.5 221,979 + Rv0190 0.37 -1.2 221,980 - Rv0190 0.37 -1.4 221,980 - Rv0190 0.37 -1.0 221,980 - Rv0190 0.37 -0.8 222,318 + -0.9 222,319 - -1.7 222,381 + +0.6 222,381 + +2.6 222,381 + -0.7 222,381 + +0.3 222,382 - +0.2 222,385 + +1.6 222,385 + -1.4 222,385 + -0.1 222,386 - -0.5 222,386 - +0.3 222,386 - +0.3 222,386 - -0.3 222,386 - -1.5 222,458 + Rv0191 0.14 -0.6 222,458 + Rv0191 0.14 -2.5 222,458 + Rv0191 0.14 +0.4 222,458 + Rv0191 0.14 +0.1 222,458 + Rv0191 0.14 -0.7 222,459 - Rv0191 0.14 -3.2 222,459 - Rv0191 0.14 -1.4 222,481 + Rv0191 0.15 +0.3 222,482 - Rv0191 0.16 -0.9
Or see this region's nucleotide sequence