Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2600

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
2,927,023	+				-2.0
2,927,023	+				-0.6
2,927,023	+				+3.7
2,927,024	-				-0.2
2,927,024	-				+0.4
2,927,024	-				+0.1
2,927,236	-		Rv2598	0.51	-0.2
2,927,424	+		Rv2598	0.88	-0.0
2,927,579	+		Rv2599	0.24	-0.7
2,927,579	+		Rv2599	0.24	+0.2
2,927,580	-		Rv2599	0.24	-0.8
2,927,678	+		Rv2599	0.47	+0.3
2,927,679	-		Rv2599	0.47	-1.1
2,927,768	+		Rv2599	0.67	-0.6
2,927,768	+		Rv2599	0.67	-0.3
2,927,769	-		Rv2599	0.68	+0.8
2,927,769	-		Rv2599	0.68	-0.2
2,927,807	+		Rv2599	0.76	+0.5
2,927,809	+		Rv2599	0.77	+0.8
2,927,822	+		Rv2599	0.80	-1.1
2,927,822	+		Rv2599	0.80	-0.7
2,927,823	-		Rv2599	0.80	-0.6
2,927,823	-		Rv2599	0.80	-0.3
2,927,906	+				+0.3
2,927,907	-				-0.4
2,927,907	-				+0.2
2,927,907	-				-0.1
2,927,937	-				-2.5
2,927,937	-				+1.2
2,927,937	-				-0.2
2,927,940	-				-1.6
2,927,940	-				-0.6
2,928,009	-				-0.6
2,928,016	-				-0.4
2,928,087	+		Rv2600	0.24	+0.2
2,928,137	+		Rv2600	0.37	+3.7
2,928,137	+		Rv2600	0.37	+0.1
2,928,137	+		Rv2600	0.37	-0.6
2,928,137	+		Rv2600	0.37	+0.5
2,928,137	+		Rv2600	0.37	+0.2
2,928,138	-		Rv2600	0.37	-0.2
2,928,173	+		Rv2600	0.46	+0.6
2,928,173	+		Rv2600	0.46	-0.7
2,928,361	-				-0.6
2,928,568	+		Rv2601	0.11	-0.5
2,928,569	-		Rv2601	0.12	-0.3
2,928,569	-		Rv2601	0.12	-1.5
2,928,569	-		Rv2601	0.12	-0.3
2,928,569	-		Rv2601	0.12	-0.1
2,928,692	-		Rv2601	0.19	+0.4
2,928,929	+		Rv2601	0.34	+0.5
2,928,930	-		Rv2601	0.34	-0.4
2,928,930	-		Rv2601	0.34	+1.2
2,929,043	+		Rv2601	0.42	+1.7
2,929,256	-		Rv2601	0.55	+0.1