Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2471

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
2,772,618	-		Rv2469c	0.38	-0.6
2,772,695	+		Rv2469c	0.49	-0.4
2,772,695	+		Rv2469c	0.49	+0.1
2,772,695	+		Rv2469c	0.49	-0.1
2,772,695	+		Rv2469c	0.49	-0.8
2,772,695	+		Rv2469c	0.49	-0.4
2,772,696	-		Rv2469c	0.49	-0.7
2,772,696	-		Rv2469c	0.49	-0.6
2,772,845	+		Rv2469c	0.71	+1.7
2,772,846	-		Rv2469c	0.72	-0.5
2,772,846	-		Rv2469c	0.72	-0.6
2,772,846	-		Rv2469c	0.72	-0.8
2,772,979	+				-0.3
2,772,980	-				-2.5
2,773,035	+				+0.3
2,773,152	-				-0.7
2,773,675	+				+0.1
2,773,675	+				+0.2
2,773,828	+		Rv2471	0.16	-0.6
2,774,020	+		Rv2471	0.28	-0.6
2,774,140	+		Rv2471	0.35	+0.5
2,774,410	+		Rv2471	0.52	+0.6
2,774,444	+		Rv2471	0.54	+0.4
2,774,470	+		Rv2471	0.55	+0.6
2,774,470	+		Rv2471	0.55	+1.7
2,774,471	-		Rv2471	0.55	+0.9
2,774,471	-		Rv2471	0.55	-0.1
2,774,993	+		Rv2471	0.87	-1.1
2,774,993	+		Rv2471	0.87	+0.1
2,774,993	+		Rv2471	0.87	+2.1
2,774,993	+		Rv2471	0.87	+0.3
2,774,997	+		Rv2471	0.87	-0.4
2,775,203	-				-0.1
2,775,203	-				+0.4
2,775,219	-				-0.7
2,775,219	-				+0.1
2,775,233	+				-0.9
2,775,233	+				-1.3
2,775,235	+				-0.1
2,775,235	+				+0.1
2,775,235	+				+0.7
2,775,236	-				+1.5
2,775,243	+				+0.3
2,775,271	+				-0.4
2,775,271	+				-0.4
2,775,272	-				-0.6
2,775,549	+				+0.1
2,775,549	+				-2.3
2,775,563	+				-0.5
2,775,697	-		Rv2473	0.18	-0.2
2,775,697	-		Rv2473	0.18	-0.3
2,775,715	+		Rv2473	0.21	+0.1
2,775,831	-		Rv2473	0.37	+0.5
2,775,851	+		Rv2473	0.39	+0.1
2,775,852	-		Rv2473	0.40	-0.6
2,776,176	-		Rv2473	0.85	+0.4
2,776,195	+		Rv2473	0.87	+0.5
2,776,196	-		Rv2473	0.88	+1.3
2,776,196	-		Rv2473	0.88	-0.7