Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1681

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
1,904,385	+				-0.3
1,904,565	-		Rv1680	0.16	-0.3
1,904,817	-		Rv1680	0.47	-0.1
1,905,070	+		Rv1680	0.78	-1.3
1,905,089	+		Rv1680	0.80	-0.2
1,905,258	-				+0.4
1,905,771	+		Rv1681	0.52	-2.4
1,905,771	+		Rv1681	0.52	-0.7
1,905,772	-		Rv1681	0.53	+0.1
1,905,772	-		Rv1681	0.53	-0.7
1,905,860	+		Rv1681	0.61	-0.6
1,905,861	-		Rv1681	0.62	-1.1
1,905,861	-		Rv1681	0.62	+0.2
1,906,094	-		Rv1681	0.85	+3.3
1,906,175	+				-0.3
1,906,175	+				-0.7
1,906,176	-				-0.7
1,906,176	-				-0.3
1,906,176	-				+0.6
1,906,240	+				-0.5
1,906,240	+				-0.6
1,906,241	-				+1.7
1,906,309	-				-0.4
1,906,466	+				+1.7
1,906,466	+				-0.7
1,906,467	-				+0.3
1,906,550	+		Rv1682	0.16	-0.2
1,906,618	-		Rv1682	0.23	+2.7
1,906,764	+		Rv1682	0.39	+0.0
1,906,765	-		Rv1682	0.39	-0.0
1,906,765	-		Rv1682	0.39	+0.3
1,906,829	-		Rv1682	0.46	+0.3
1,907,230	+				+1.7