Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1250

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 1.5 mM; pH 5.5
1,393,218	+				-0.5
1,393,219	-				+0.0
1,393,400	-		Rv1249c	0.26	-0.3
1,393,400	-		Rv1249c	0.26	-0.1
1,393,400	-		Rv1249c	0.26	-0.0
1,393,400	-		Rv1249c	0.26	+0.7
1,393,514	+		Rv1249c	0.41	+0.3
1,393,587	+		Rv1249c	0.50	-0.6
1,393,687	-		Rv1249c	0.62	-0.7
1,393,705	-		Rv1249c	0.65	-0.1
1,393,705	-		Rv1249c	0.65	-0.6
1,393,705	-		Rv1249c	0.65	-0.5
1,393,810	+		Rv1249c	0.78	+0.4
1,393,810	+		Rv1249c	0.78	+0.2
1,393,810	+		Rv1249c	0.78	+0.1
1,393,810	+		Rv1249c	0.78	-0.2
1,393,810	+		Rv1249c	0.78	-0.6
1,393,810	+		Rv1249c	0.78	-1.2
1,393,810	+		Rv1249c	0.78	-0.1
1,393,810	+		Rv1249c	0.78	-0.5
1,393,810	+		Rv1249c	0.78	+0.4
1,393,810	+		Rv1249c	0.78	-0.1
1,393,811	-		Rv1249c	0.78	-0.3
1,393,811	-		Rv1249c	0.78	-0.1
1,394,079	+				+0.2
1,394,178	+				-1.3
1,394,179	-				-0.7
1,394,179	-				-0.1
1,394,179	-				+0.3
1,394,185	-				-0.6
1,394,216	-				+0.0
1,394,292	-				+1.7
1,394,325	-				-0.2
1,394,365	+		Rv1250	0.11	-0.3
1,394,377	+		Rv1250	0.11	+1.4
1,394,551	-		Rv1250	0.21	+0.0
1,394,769	-		Rv1250	0.34	-0.2
1,394,847	-		Rv1250	0.38	-0.0
1,395,064	+		Rv1250	0.51	-2.3
1,395,065	-		Rv1250	0.51	+0.0
1,395,602	+		Rv1250	0.82	+0.6
1,395,703	+		Rv1250	0.88	-0.5
1,395,713	-		Rv1250	0.88	-0.1
1,395,889	-				-0.4
1,395,914	+				-1.0
1,395,914	+				-0.8
1,395,927	+				-1.1
1,396,071	-				-0.6
1,396,076	+				-0.6
1,396,144	-				-0.1
1,396,298	-		Rv1251c	0.14	+0.1
1,396,372	-		Rv1251c	0.16	-0.1
1,396,417	-		Rv1251c	0.17	-1.2
1,396,428	-		Rv1251c	0.18	-0.7
1,396,523	+		Rv1251c	0.21	-1.0
1,396,729	-		Rv1251c	0.27	-1.1