Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0972c

Experiment: 7H9 with nitrite 1.5 mM; pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0970 and Rv0971c are separated by 90 nucleotidesRv0971c and Rv0972c overlap by 1 nucleotidesRv0972c and Rv0973c overlap by 4 nucleotides Rv0970: Rv0970 - Probable conserved integral membrane protein, at 1,081,052 to 1,081,684 Rv0970 Rv0971c: Rv0971c - Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,081,775 to 1,082,584 Rv0971c Rv0972c: Rv0972c - Acyl-CoA dehydrogenase FadE12, at 1,082,584 to 1,083,750 Rv0972c Rv0973c: Rv0973c - Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrier protein (BCCP), at 1,083,747 to 1,085,750 Rv0973c Position (kb) 1082 1083 1084Strain fitness (log2 ratio) -1 0 1 2 3at 1081.620 kb on + strand, within Rv0970at 1081.620 kb on + strand, within Rv0970at 1081.620 kb on + strand, within Rv0970at 1081.645 kb on + strandat 1081.755 kb on + strandat 1082.088 kb on + strand, within Rv0971cat 1082.089 kb on - strand, within Rv0971cat 1082.089 kb on - strand, within Rv0971cat 1082.089 kb on - strand, within Rv0971cat 1082.091 kb on + strand, within Rv0971cat 1082.091 kb on + strand, within Rv0971cat 1082.469 kb on - strand, within Rv0971cat 1082.588 kb on + strandat 1082.777 kb on + strand, within Rv0972cat 1082.777 kb on + strand, within Rv0972cat 1082.778 kb on - strand, within Rv0972cat 1083.205 kb on + strand, within Rv0972cat 1083.543 kb on - strand, within Rv0972cat 1083.811 kb on - strandat 1084.519 kb on - strand, within Rv0973cat 1084.567 kb on + strand, within Rv0973cat 1084.567 kb on + strand, within Rv0973cat 1084.568 kb on - strand, within Rv0973c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 1.5 mM; pH 5.5
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1,081,620 + Rv0970 0.90 -0.3
1,081,620 + Rv0970 0.90 +0.1
1,081,620 + Rv0970 0.90 +0.6
1,081,645 + +0.5
1,081,755 + -0.8
1,082,088 + Rv0971c 0.39 +0.1
1,082,089 - Rv0971c 0.39 +1.3
1,082,089 - Rv0971c 0.39 +1.3
1,082,089 - Rv0971c 0.39 +1.0
1,082,091 + Rv0971c 0.39 -0.1
1,082,091 + Rv0971c 0.39 +0.3
1,082,469 - Rv0971c 0.86 +3.0
1,082,588 + +0.4
1,082,777 + Rv0972c 0.17 -0.6
1,082,777 + Rv0972c 0.17 -0.4
1,082,778 - Rv0972c 0.17 -1.2
1,083,205 + Rv0972c 0.53 -1.7
1,083,543 - Rv0972c 0.82 -0.5
1,083,811 - -0.6
1,084,519 - Rv0973c 0.39 -0.5
1,084,567 + Rv0973c 0.41 +1.1
1,084,567 + Rv0973c 0.41 -0.5
1,084,568 - Rv0973c 0.41 -0.2

Or see this region's nucleotide sequence