Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3737

Experiment: 7H9 with nitrite 3 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 3 mM; pH 5.5
4,186,946	+		Rv3736	0.29	+1.6
4,186,946	+		Rv3736	0.29	+0.1
4,186,946	+		Rv3736	0.29	-0.1
4,186,958	-		Rv3736	0.31	-0.6
4,186,958	-		Rv3736	0.31	+0.6
4,186,999	+		Rv3736	0.34	-0.4
4,186,999	+		Rv3736	0.34	-0.3
4,187,000	-		Rv3736	0.34	-0.4
4,187,105	+		Rv3736	0.44	-1.3
4,187,106	-		Rv3736	0.44	-3.2
4,187,106	-		Rv3736	0.44	-0.2
4,187,106	-		Rv3736	0.44	+0.3
4,187,127	+		Rv3736	0.46	-0.4
4,187,127	+		Rv3736	0.46	-0.2
4,187,159	+		Rv3736	0.49	-1.6
4,187,160	-		Rv3736	0.50	+0.2
4,187,168	+		Rv3736	0.50	+1.6
4,187,168	+		Rv3736	0.50	-0.0
4,187,169	-		Rv3736	0.50	-0.2
4,187,186	+		Rv3736	0.52	+0.4
4,187,283	-		Rv3736	0.61	+0.7
4,187,453	-		Rv3736	0.77	+0.3
4,187,492	+		Rv3736	0.81	+0.5
4,187,496	+		Rv3736	0.81	-1.4
4,187,496	+		Rv3736	0.81	-0.2
4,187,496	+		Rv3736	0.81	+1.6
4,187,497	-		Rv3736	0.81	+1.6
4,187,625	+				-0.6
4,187,626	-				+0.2
4,187,674	+				+0.1
4,187,675	-				+0.1
4,187,686	-				+0.4
4,188,374	+		Rv3737	0.42	+0.2
4,188,374	+		Rv3737	0.42	+1.2
4,188,480	-		Rv3737	0.49	-0.2
4,188,702	-		Rv3737	0.63	-0.3
4,188,702	-		Rv3737	0.63	+1.3
4,188,702	-		Rv3737	0.63	+0.3
4,188,711	+		Rv3737	0.64	-1.3
4,189,258	+				-0.0
4,189,568	-		Rv3738c	0.30	+0.1
4,189,598	-		Rv3738c	0.33	-0.8
4,189,842	-		Rv3738c	0.59	-0.5
4,189,842	-		Rv3738c	0.59	+0.2
4,190,048	+		Rv3738c	0.80	-0.4
4,190,048	+		Rv3738c	0.80	-0.5
4,190,049	-		Rv3738c	0.81	-0.6
4,190,049	-		Rv3738c	0.81	-2.2
4,190,049	-		Rv3738c	0.81	+0.4
4,190,049	-		Rv3738c	0.81	+1.3
4,190,052	+		Rv3738c	0.81	-0.4
4,190,052	+		Rv3738c	0.81	-0.4
4,190,052	+		Rv3738c	0.81	-0.4
4,190,052	+		Rv3738c	0.81	-0.3
4,190,052	+		Rv3738c	0.81	-0.1
4,190,052	+		Rv3738c	0.81	-0.0
4,190,052	+		Rv3738c	0.81	+1.6
4,190,053	-		Rv3738c	0.81	+0.1
4,190,090	+		Rv3738c	0.85	+0.1
4,190,091	-		Rv3738c	0.85	-1.5
4,190,091	-		Rv3738c	0.85	+0.8
4,190,122	-		Rv3738c	0.88	-0.3
4,190,173	-				-1.2
4,190,219	+				-0.3
4,190,219	+				-0.7
4,190,232	+				-0.6
4,190,233	-				-0.6