Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3125c

Experiment: 7H9 with nitrite 3 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 3 mM; pH 5.5
3,489,522	+				-0.3
3,489,522	+				-0.5
3,489,522	+				+0.2
3,489,522	+				+0.3
3,489,523	-				-2.5
3,489,523	-				-0.4
3,489,538	-				+0.2
3,489,538	-				-0.5
3,489,698	+		Rv3124	0.22	-0.7
3,489,698	+		Rv3124	0.22	+0.1
3,489,698	+		Rv3124	0.22	-1.1
3,490,124	+		Rv3124	0.71	-1.0
3,490,137	-		Rv3124	0.73	-0.0
3,490,219	-		Rv3124	0.82	+1.2
3,490,324	-				+0.7
3,490,324	-				-0.6
3,490,374	-				-0.5
3,490,377	+				+0.6
3,490,377	+				+0.5
3,490,377	+				-0.1
3,490,377	+				+0.4
3,490,377	+				+0.5
3,490,377	+				+0.2
3,490,377	+				-0.1
3,490,378	-				+0.4
3,490,378	-				-0.5
3,490,378	-				+0.9
3,490,378	-				-1.4
3,490,378	-				-1.5
3,490,378	-				+0.3
3,490,461	+				-0.6
3,490,462	-				-0.7
3,490,478	-				-0.6
3,490,478	-				-0.4
3,490,586	+				-0.4
3,490,587	-				-0.7
3,490,614	-		Rv3125c	0.12	-1.0
3,490,614	-		Rv3125c	0.12	+0.3
3,490,614	-		Rv3125c	0.12	-0.3
3,490,658	+		Rv3125c	0.15	+0.5
3,490,659	-		Rv3125c	0.16	+0.0
3,490,765	-		Rv3125c	0.25	-0.3
3,490,847	+		Rv3125c	0.32	+0.0
3,490,881	+		Rv3125c	0.34	+0.9
3,490,907	+		Rv3125c	0.37	-0.6
3,491,141	+		Rv3125c	0.57	+1.1
3,491,186	-		Rv3125c	0.60	+1.2
3,491,431	+		Rv3125c	0.81	+1.3
3,491,432	-		Rv3125c	0.81	+0.6
3,491,545	-				+0.8
3,491,691	-				-0.1
3,491,691	-				-1.3
3,492,142	+				-1.1
3,492,142	+				-1.2
3,492,142	+				+1.6
3,492,525	+		Rv3127	0.37	-0.5