Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3074

Experiment: 7H9 with nitrite 3 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 3 mM; pH 5.5
3,435,845	-				-0.2
3,435,949	-		Rv3072c	0.29	-0.6
3,436,144	+		Rv3072c	0.66	-0.2
3,436,145	-		Rv3072c	0.66	-0.9
3,436,269	+		Rv3072c	0.90	+1.1
3,436,270	-				-0.8
3,436,472	-		Rv3073c	0.40	-0.4
3,436,649	-		Rv3073c	0.90	+0.6
3,436,696	+				+0.6
3,436,699	-				+0.1
3,436,860	-				+0.8
3,437,162	-		Rv3074	0.30	-0.4
3,437,174	-		Rv3074	0.31	+1.6
3,437,174	-		Rv3074	0.31	+0.9
3,437,174	-		Rv3074	0.31	+0.6
3,437,174	-		Rv3074	0.31	-0.3
3,437,245	-		Rv3074	0.37	-0.4
3,437,300	+		Rv3074	0.41	+1.2
3,437,300	+		Rv3074	0.41	+0.0
3,437,300	+		Rv3074	0.41	-0.4
3,437,337	+		Rv3074	0.44	-0.5
3,437,337	+		Rv3074	0.44	-1.6
3,437,337	+		Rv3074	0.44	+0.7
3,437,338	-		Rv3074	0.44	-0.1
3,437,379	+		Rv3074	0.47	-0.0
3,437,379	+		Rv3074	0.47	+0.5
3,437,379	+		Rv3074	0.47	-0.4
3,437,655	+		Rv3074	0.69	-0.2
3,437,656	-		Rv3074	0.69	+0.9
3,437,656	-		Rv3074	0.69	-0.0
3,437,766	+		Rv3074	0.77	+0.4
3,437,767	-		Rv3074	0.77	+0.1
3,438,054	+				-0.5
3,438,060	+				-1.0
3,438,123	+				+0.4
3,438,592	+		Rv3075c	0.59	+0.6
3,438,592	+		Rv3075c	0.59	-0.0
3,438,592	+		Rv3075c	0.59	-0.7
3,438,592	+		Rv3075c	0.59	+0.1
3,438,592	+		Rv3075c	0.59	+0.1
3,438,593	-		Rv3075c	0.59	-0.0
3,438,683	+		Rv3075c	0.69	-0.2
3,438,960	+				-0.2
3,438,960	+				-2.3
3,438,960	+				-0.3
3,438,960	+				-1.4
3,438,976	-				+0.3
3,439,015	+				-0.3
3,439,016	-				-0.0
3,439,016	-				-0.7