Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3639c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3637 and Rv3638 overlap by 1 nucleotidesRv3638 and Rv3639c are separated by 153 nucleotidesRv3639c and Rv3640c are separated by 69 nucleotides Rv3637: Rv3637 - Possible transposase, at 4,076,484 to 4,076,984 Rv3637 Rv3638: Rv3638 - Possible transposase, at 4,076,984 to 4,077,730 Rv3638 Rv3639c: Rv3639c - Conserved hypothetical protein, at 4,077,884 to 4,078,450 Rv3639c Rv3640c: Rv3640c - Probable transposase, at 4,078,520 to 4,079,749 Rv3640c Position (kb) 4077 4078 4079Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 4076.946 kb on + strandat 4076.946 kb on + strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4076.947 kb on - strandat 4077.035 kb on + strandat 4077.119 kb on + strand, within Rv3638at 4077.120 kb on - strand, within Rv3638at 4077.120 kb on - strand, within Rv3638at 4077.120 kb on - strand, within Rv3638at 4077.273 kb on + strand, within Rv3638at 4077.306 kb on + strand, within Rv3638at 4077.306 kb on + strand, within Rv3638at 4077.473 kb on + strand, within Rv3638at 4077.473 kb on + strand, within Rv3638at 4077.473 kb on + strand, within Rv3638at 4077.562 kb on + strand, within Rv3638at 4077.588 kb on + strand, within Rv3638at 4077.672 kb on - strandat 4077.790 kb on + strandat 4077.791 kb on - strandat 4077.792 kb on - strandat 4077.939 kb on + strandat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4078.521 kb on + strandat 4078.522 kb on - strandat 4078.583 kb on - strandat 4078.720 kb on + strand, within Rv3640cat 4078.720 kb on + strand, within Rv3640cat 4078.793 kb on + strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.259 kb on + strand, within Rv3640cat 4079.413 kb on + strand, within Rv3640cat 4079.414 kb on - strand, within Rv3640cat 4079.424 kb on + strand, within Rv3640c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
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4,076,946 + -1.3
4,076,946 + -0.2
4,076,947 - -0.6
4,076,947 - -0.2
4,076,947 - +0.4
4,076,947 - -3.4
4,076,947 - -0.0
4,077,035 + -0.1
4,077,119 + Rv3638 0.18 +2.2
4,077,120 - Rv3638 0.18 +0.4
4,077,120 - Rv3638 0.18 -0.3
4,077,120 - Rv3638 0.18 +0.3
4,077,273 + Rv3638 0.39 +0.1
4,077,306 + Rv3638 0.43 +0.4
4,077,306 + Rv3638 0.43 +0.1
4,077,473 + Rv3638 0.65 +0.7
4,077,473 + Rv3638 0.65 +0.7
4,077,473 + Rv3638 0.65 -0.8
4,077,562 + Rv3638 0.77 -0.7
4,077,588 + Rv3638 0.81 +0.4
4,077,672 - -0.2
4,077,790 + +0.4
4,077,791 - +1.2
4,077,792 - +0.6
4,077,939 + -0.2
4,077,957 + Rv3639c 0.13 -0.6
4,077,957 + Rv3639c 0.13 -2.5
4,077,957 + Rv3639c 0.13 +3.4
4,077,957 + Rv3639c 0.13 +1.0
4,077,958 - Rv3639c 0.13 +0.0
4,077,958 - Rv3639c 0.13 -1.6
4,077,958 - Rv3639c 0.13 +1.8
4,077,958 - Rv3639c 0.13 -1.5
4,077,958 - Rv3639c 0.13 +2.5
4,078,521 + +1.0
4,078,522 - -2.0
4,078,583 - +0.3
4,078,720 + Rv3640c 0.16 -0.1
4,078,720 + Rv3640c 0.16 +0.1
4,078,793 + Rv3640c 0.22 -0.1
4,079,245 - Rv3640c 0.59 +0.5
4,079,245 - Rv3640c 0.59 +1.2
4,079,245 - Rv3640c 0.59 -0.0
4,079,245 - Rv3640c 0.59 -0.0
4,079,259 + Rv3640c 0.60 -1.0
4,079,413 + Rv3640c 0.73 -0.4
4,079,414 - Rv3640c 0.73 -0.5
4,079,424 + Rv3640c 0.73 -1.5

Or see this region's nucleotide sequence