Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3408

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
3,825,648	+		Rv3406	0.36	+0.2
3,825,648	+		Rv3406	0.36	-0.2
3,825,648	+		Rv3406	0.36	+1.0
3,825,649	-		Rv3406	0.36	+0.1
3,825,729	+		Rv3406	0.45	-0.2
3,825,801	+		Rv3406	0.53	-0.6
3,825,801	+		Rv3406	0.53	+1.4
3,825,801	+		Rv3406	0.53	+1.4
3,825,802	-		Rv3406	0.53	+0.7
3,825,802	-		Rv3406	0.53	-2.9
3,825,802	-		Rv3406	0.53	-0.3
3,825,802	-		Rv3406	0.53	-0.9
3,825,895	+		Rv3406	0.64	-0.7
3,825,925	+		Rv3406	0.67	-0.3
3,825,925	+		Rv3406	0.67	-0.1
3,825,926	-		Rv3406	0.67	+0.4
3,826,054	+		Rv3406	0.82	+0.8
3,826,054	+		Rv3406	0.82	+1.4
3,826,102	-		Rv3406	0.87	-0.1
3,826,175	+				-0.6
3,826,242	-				-0.7
3,826,298	+		Rv3407	0.15	-0.2
3,826,298	+		Rv3407	0.15	+0.9
3,826,298	+		Rv3407	0.15	-0.4
3,826,299	-		Rv3407	0.16	-0.0
3,826,554	+				-0.3
3,826,554	+				+0.8
3,826,555	-				-0.2
3,826,555	-				-0.1
3,826,555	-				-1.7
3,826,555	-				+0.6
3,826,555	-				-0.6
3,826,557	-				-0.4
3,826,738	-		Rv3408	0.46	+0.3
3,826,742	-		Rv3408	0.47	+0.9
3,826,742	-		Rv3408	0.47	-2.1
3,826,817	-		Rv3408	0.65	+0.5
3,826,817	-		Rv3408	0.65	+0.7
3,826,817	-		Rv3408	0.65	+0.0
3,826,817	-		Rv3408	0.65	+0.3
3,826,962	+				+1.8
3,827,232	+		Rv3409c	0.14	-0.6
3,827,250	+		Rv3409c	0.15	+0.6
3,827,250	+		Rv3409c	0.15	+0.1
3,827,250	+		Rv3409c	0.15	+0.3
3,827,250	+		Rv3409c	0.15	-0.2
3,827,251	-		Rv3409c	0.15	-0.7
3,827,251	-		Rv3409c	0.15	-1.2
3,827,262	+		Rv3409c	0.16	+0.5
3,827,426	-		Rv3409c	0.25	+0.2
3,827,426	-		Rv3409c	0.25	+0.7
3,827,426	-		Rv3409c	0.25	-0.8
3,827,882	-		Rv3409c	0.51	+0.4