Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2189c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2188c and Rv2189c are separated by 96 nucleotidesRv2189c and Rv2190c are separated by 94 nucleotides Rv2188c: Rv2188c - Mannosyltransferase PimB, at 2,449,993 to 2,451,150 Rv2188c Rv2189c: Rv2189c - Conserved hypothetical protein, at 2,451,247 to 2,452,020 Rv2189c Rv2190c: Rv2190c - Conserved hypothetical protein, at 2,452,115 to 2,453,272 Rv2190c Position (kb) 2451 2452 2453Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 2451.249 kb on - strandat 2451.256 kb on + strandat 2451.257 kb on - strandat 2451.381 kb on + strand, within Rv2189cat 2451.386 kb on + strand, within Rv2189cat 2451.387 kb on - strand, within Rv2189cat 2451.428 kb on + strand, within Rv2189cat 2452.026 kb on + strandat 2452.027 kb on - strandat 2452.183 kb on - strandat 2452.183 kb on - strandat 2452.183 kb on - strandat 2452.219 kb on - strandat 2452.659 kb on + strand, within Rv2190cat 2452.849 kb on + strand, within Rv2190cat 2452.928 kb on - strand, within Rv2190cat 2452.941 kb on + strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
remove
2,451,249 - +3.8
2,451,256 + +0.8
2,451,257 - +0.2
2,451,381 + Rv2189c 0.17 -1.3
2,451,386 + Rv2189c 0.18 -0.8
2,451,387 - Rv2189c 0.18 -1.5
2,451,428 + Rv2189c 0.23 -0.3
2,452,026 + +2.8
2,452,027 - -0.8
2,452,183 - -1.2
2,452,183 - +1.0
2,452,183 - -1.1
2,452,219 - +1.2
2,452,659 + Rv2190c 0.47 +1.8
2,452,849 + Rv2190c 0.63 -0.1
2,452,928 - Rv2190c 0.70 +0.3
2,452,941 + Rv2190c 0.71 -2.0
2,452,942 - Rv2190c 0.71 -1.7
2,452,942 - Rv2190c 0.71 -1.4
2,452,942 - Rv2190c 0.71 -0.2
2,452,942 - Rv2190c 0.71 -1.9

Or see this region's nucleotide sequence