Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3821

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
4,284,982	+		Rv3820c	0.40	-0.4
4,284,983	-		Rv3820c	0.40	+0.3
4,285,055	-		Rv3820c	0.45	-0.6
4,285,082	+		Rv3820c	0.47	-0.1
4,285,083	-		Rv3820c	0.47	+0.2
4,285,194	+		Rv3820c	0.55	+1.1
4,285,194	+		Rv3820c	0.55	+0.2
4,285,272	+		Rv3820c	0.61	+0.4
4,285,273	-		Rv3820c	0.61	+0.8
4,285,273	-		Rv3820c	0.61	+0.8
4,285,279	+		Rv3820c	0.61	+0.2
4,285,280	-		Rv3820c	0.61	+0.4
4,285,280	-		Rv3820c	0.61	+0.8
4,285,345	-		Rv3820c	0.66	+1.1
4,285,345	-		Rv3820c	0.66	+0.8
4,285,498	+		Rv3820c	0.77	+0.6
4,285,499	-		Rv3820c	0.77	-0.5
4,285,546	-		Rv3820c	0.80	+0.1
4,285,546	-		Rv3820c	0.80	+0.4
4,285,582	-		Rv3820c	0.83	+0.5
4,285,645	+		Rv3820c	0.87	-1.0
4,285,661	+		Rv3820c	0.88	-2.0
4,285,661	+		Rv3820c	0.88	+0.0
4,285,662	-		Rv3820c	0.88	-0.6
4,285,674	+		Rv3820c	0.89	+1.6
4,285,702	-				-0.6
4,285,722	-				-1.0
4,285,722	-				-0.4
4,285,722	-				-0.9
4,285,774	+				+0.4
4,285,774	+				+3.2
4,285,775	-				+1.2
4,285,813	+				-0.6
4,285,813	+				-0.6
4,285,814	-				+0.6
4,285,814	-				-0.1
4,285,819	+				+0.2
4,285,819	+				-1.3
4,285,820	-				+0.2
4,285,820	-				-0.4
4,285,820	-				+1.0
4,285,870	+				-0.1
4,285,875	+				+0.9
4,285,875	+				+1.2
4,285,911	+				-1.1
4,285,911	+				+0.5
4,286,099	+		Rv3821	0.18	+0.1
4,286,185	-		Rv3821	0.30	+0.8
4,286,216	-		Rv3821	0.34	+0.2
4,286,244	+		Rv3821	0.38	+0.3
4,286,245	-		Rv3821	0.38	-0.9
4,286,245	-		Rv3821	0.38	+0.6
4,286,245	-		Rv3821	0.38	-1.1
4,286,304	+		Rv3821	0.46	+1.6
4,286,336	-		Rv3821	0.51	+0.2
4,286,336	-		Rv3821	0.51	+0.4
4,286,381	+		Rv3821	0.57	+0.1
4,286,403	+		Rv3821	0.60	+0.3
4,286,404	-		Rv3821	0.60	+1.2
4,286,429	+		Rv3821	0.64	+0.7
4,286,429	+		Rv3821	0.64	+0.3
4,286,430	-		Rv3821	0.64	-0.8
4,286,497	+		Rv3821	0.73	-0.2
4,286,497	+		Rv3821	0.73	-1.1
4,286,546	+		Rv3821	0.80	-1.2
4,286,563	+		Rv3821	0.83	-1.2
4,286,563	+		Rv3821	0.83	+1.4
4,286,563	+		Rv3821	0.83	+1.6
4,286,759	-				-1.1
4,286,891	+		Rv3822	0.14	-0.6
4,286,892	-		Rv3822	0.14	+0.8
4,286,893	+		Rv3822	0.14	-0.3
4,286,932	+		Rv3822	0.17	+1.3
4,286,933	-		Rv3822	0.17	-0.4
4,286,935	+		Rv3822	0.18	+1.2
4,286,980	-		Rv3822	0.21	-0.1
4,287,021	+		Rv3822	0.25	+0.1
4,287,022	-		Rv3822	0.25	-0.5
4,287,024	+		Rv3822	0.25	-0.6
4,287,025	-		Rv3822	0.25	-0.2
4,287,025	-		Rv3822	0.25	-0.2
4,287,025	-		Rv3822	0.25	+0.5
4,287,288	-		Rv3822	0.47	+0.9
4,287,399	+		Rv3822	0.56	-1.3
4,287,400	-		Rv3822	0.56	-0.5
4,287,440	-		Rv3822	0.59	-1.2
4,287,477	+		Rv3822	0.62	-1.0
4,287,477	+		Rv3822	0.62	+0.6
4,287,478	-		Rv3822	0.62	-1.8
4,287,478	-		Rv3822	0.62	-1.2
4,287,533	+		Rv3822	0.67	+0.2
4,287,533	+		Rv3822	0.67	+0.8
4,287,533	+		Rv3822	0.67	-0.4
4,287,573	+		Rv3822	0.70	+1.5
4,287,574	-		Rv3822	0.70	-0.9
4,287,574	-		Rv3822	0.70	-0.5
4,287,574	-		Rv3822	0.70	+1.4
4,287,574	-		Rv3822	0.70	-1.0
4,287,574	-		Rv3822	0.70	+0.8
4,287,596	-		Rv3822	0.72	-0.2
4,287,596	-		Rv3822	0.72	-0.1