Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2969c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2967c and Rv2968c are separated by 24 nucleotidesRv2968c and Rv2969c are separated by 5 nucleotidesRv2969c and Rv2970c are separated by 96 nucleotides Rv2967c: Rv2967c - Probable pyruvate carboxylase Pca (pyruvic carboxylase), at 3,319,663 to 3,323,046 Rv2967c Rv2968c: Rv2968c - Probable conserved integral membrane protein, at 3,323,071 to 3,323,703 Rv2968c Rv2969c: Rv2969c - Possible conserved membrane or secreted protein, at 3,323,709 to 3,324,476 Rv2969c Rv2970c: Rv2970c - Probable lipase/esterase LipN, at 3,324,573 to 3,325,703 Rv2970c Position (kb) 3323 3324 3325Strain fitness (log2 ratio) -3 -2 -1 0 1at 3322.808 kb on + strandat 3322.812 kb on + strandat 3322.865 kb on + strandat 3322.865 kb on + strandat 3322.865 kb on + strandat 3322.866 kb on - strandat 3322.866 kb on - strandat 3322.946 kb on + strandat 3322.953 kb on - strandat 3324.545 kb on - strandat 3324.550 kb on - strandat 3324.585 kb on - strandat 3324.731 kb on - strand, within Rv2970cat 3324.862 kb on + strand, within Rv2970cat 3324.862 kb on + strand, within Rv2970cat 3324.862 kb on + strand, within Rv2970cat 3324.863 kb on - strand, within Rv2970cat 3325.001 kb on - strand, within Rv2970cat 3325.125 kb on + strand, within Rv2970cat 3325.138 kb on + strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.139 kb on - strand, within Rv2970cat 3325.200 kb on + strand, within Rv2970cat 3325.200 kb on + strand, within Rv2970cat 3325.286 kb on - strand, within Rv2970cat 3325.328 kb on - strand, within Rv2970cat 3325.417 kb on - strand, within Rv2970c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
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3,322,808 + -1.7
3,322,812 + -2.9
3,322,865 + -0.5
3,322,865 + +0.4
3,322,865 + -3.5
3,322,866 - -0.5
3,322,866 - -1.1
3,322,946 + -0.3
3,322,953 - -0.6
3,324,545 - -0.0
3,324,550 - -1.1
3,324,585 - -1.1
3,324,731 - Rv2970c 0.14 -0.7
3,324,862 + Rv2970c 0.26 +1.1
3,324,862 + Rv2970c 0.26 +1.4
3,324,862 + Rv2970c 0.26 -0.0
3,324,863 - Rv2970c 0.26 -0.5
3,325,001 - Rv2970c 0.38 -1.1
3,325,125 + Rv2970c 0.49 +0.5
3,325,138 + Rv2970c 0.50 -0.4
3,325,139 - Rv2970c 0.50 -1.6
3,325,139 - Rv2970c 0.50 -0.2
3,325,139 - Rv2970c 0.50 -1.2
3,325,200 + Rv2970c 0.55 -0.2
3,325,200 + Rv2970c 0.55 -0.7
3,325,286 - Rv2970c 0.63 +0.3
3,325,328 - Rv2970c 0.67 +0.7
3,325,417 - Rv2970c 0.75 -0.1

Or see this region's nucleotide sequence