Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2591 and Rv2592c are separated by 16 nucleotides Rv2592c and Rv2593c overlap by 4 nucleotides Rv2593c and Rv2594c overlap by 4 nucleotides
Rv2591: Rv2591 - PE-PGRS family protein PE_PGRS44, at 2,921,551 to 2,923,182
Rv2591
Rv2592c: Rv2592c - Probable holliday junction DNA helicase RuvB, at 2,923,199 to 2,924,233
Rv2592c
Rv2593c: Rv2593c - Probable holliday junction DNA helicase RuvA, at 2,924,230 to 2,924,820
Rv2593c
Rv2594c: Rv2594c - Probable crossover junction endodeoxyribonuclease RuvC (holliday junction nuclease) (holliday junction resolvase), at 2,924,817 to 2,925,383
Rv2594c
Position (kb)
2923
2924
2925 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2922.389 kb on + strand, within Rv2591 at 2922.390 kb on - strand, within Rv2591 at 2922.390 kb on - strand, within Rv2591 at 2922.390 kb on - strand, within Rv2591 at 2922.631 kb on - strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2922.969 kb on + strand, within Rv2591 at 2923.200 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 remove 2,922,389 + Rv2591 0.51 -0.1 2,922,390 - Rv2591 0.51 -0.2 2,922,390 - Rv2591 0.51 -0.5 2,922,390 - Rv2591 0.51 +1.1 2,922,631 - Rv2591 0.66 -0.5 2,922,969 + Rv2591 0.87 +0.5 2,922,969 + Rv2591 0.87 +3.3 2,922,969 + Rv2591 0.87 +0.2 2,922,969 + Rv2591 0.87 -0.4 2,922,969 + Rv2591 0.87 -2.5 2,922,969 + Rv2591 0.87 -0.6 2,922,969 + Rv2591 0.87 +0.3 2,923,200 + -0.3
Or see this region's nucleotide sequence