Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1666c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1665 and Rv1666c overlap by 18 nucleotidesRv1666c and Rv1667c are separated by 14 nucleotidesRv1667c and Rv1668c overlap by 7 nucleotides Rv1665: Rv1665 - Chalcone synthase Pks11, at 1,891,226 to 1,892,287 Rv1665 Rv1666c: Rv1666c - Probable cytochrome P450 139 Cyp139, at 1,892,270 to 1,893,562 Rv1666c Rv1667c: Rv1667c - Probable second part of macrolide-transport ATP-binding protein ABC transporter, at 1,893,577 to 1,894,230 Rv1667c Rv1668c: Rv1668c - Probable first part of macrolide-transport ATP-binding protein ABC transporter, at 1,894,224 to 1,895,342 Rv1668c Position (kb) 1892 1893 1894Strain fitness (log2 ratio) -2 -1 0 1 2at 1891.401 kb on - strand, within Rv1665at 1891.677 kb on - strand, within Rv1665at 1891.740 kb on - strand, within Rv1665at 1891.980 kb on - strand, within Rv1665at 1892.179 kb on + strand, within Rv1665at 1892.180 kb on - strand, within Rv1665at 1892.180 kb on - strand, within Rv1665at 1892.180 kb on - strand, within Rv1665at 1892.262 kb on - strandat 1892.271 kb on + strandat 1892.272 kb on - strandat 1892.583 kb on + strand, within Rv1666cat 1892.584 kb on - strand, within Rv1666cat 1892.715 kb on + strand, within Rv1666cat 1892.716 kb on - strand, within Rv1666cat 1892.820 kb on + strand, within Rv1666cat 1892.911 kb on + strand, within Rv1666cat 1892.911 kb on + strand, within Rv1666cat 1892.912 kb on - strand, within Rv1666cat 1893.146 kb on + strand, within Rv1666cat 1893.146 kb on + strand, within Rv1666cat 1893.213 kb on + strand, within Rv1666cat 1893.213 kb on + strand, within Rv1666cat 1893.213 kb on + strand, within Rv1666cat 1893.214 kb on - strand, within Rv1666cat 1893.214 kb on - strand, within Rv1666cat 1893.262 kb on + strand, within Rv1666cat 1893.471 kb on + strandat 1893.471 kb on + strandat 1893.472 kb on - strandat 1893.472 kb on - strandat 1893.477 kb on + strandat 1893.477 kb on + strandat 1893.477 kb on + strandat 1893.478 kb on - strandat 1893.478 kb on - strandat 1893.478 kb on - strandat 1893.525 kb on + strandat 1893.571 kb on - strandat 1893.571 kb on - strandat 1893.571 kb on - strandat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.646 kb on + strand, within Rv1667cat 1893.647 kb on - strand, within Rv1667cat 1893.647 kb on - strand, within Rv1667cat 1893.647 kb on - strand, within Rv1667cat 1893.647 kb on - strand, within Rv1667cat 1893.647 kb on - strand, within Rv1667cat 1893.708 kb on + strand, within Rv1667cat 1893.864 kb on - strand, within Rv1667cat 1893.914 kb on + strand, within Rv1667cat 1893.972 kb on + strand, within Rv1667cat 1894.166 kb on - strandat 1894.166 kb on - strandat 1894.166 kb on - strandat 1894.225 kb on + strandat 1894.457 kb on - strand, within Rv1668cat 1894.457 kb on - strand, within Rv1668c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
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1,891,401 - Rv1665 0.16 -1.8
1,891,677 - Rv1665 0.42 -0.2
1,891,740 - Rv1665 0.48 -0.2
1,891,980 - Rv1665 0.71 +1.7
1,892,179 + Rv1665 0.90 +0.2
1,892,180 - Rv1665 0.90 +0.0
1,892,180 - Rv1665 0.90 -2.7
1,892,180 - Rv1665 0.90 +0.5
1,892,262 - -0.2
1,892,271 + +0.7
1,892,272 - -0.4
1,892,583 + Rv1666c 0.24 +0.7
1,892,584 - Rv1666c 0.24 -2.0
1,892,715 + Rv1666c 0.34 -1.0
1,892,716 - Rv1666c 0.34 -0.4
1,892,820 + Rv1666c 0.43 -0.2
1,892,911 + Rv1666c 0.50 +0.9
1,892,911 + Rv1666c 0.50 -1.3
1,892,912 - Rv1666c 0.50 -0.5
1,893,146 + Rv1666c 0.68 -1.3
1,893,146 + Rv1666c 0.68 +0.1
1,893,213 + Rv1666c 0.73 +0.8
1,893,213 + Rv1666c 0.73 -1.2
1,893,213 + Rv1666c 0.73 -1.5
1,893,214 - Rv1666c 0.73 -0.9
1,893,214 - Rv1666c 0.73 -0.2
1,893,262 + Rv1666c 0.77 -0.3
1,893,471 + -0.2
1,893,471 + +0.7
1,893,472 - -0.6
1,893,472 - +0.2
1,893,477 + -0.9
1,893,477 + +2.7
1,893,477 + +0.5
1,893,478 - +0.9
1,893,478 - -0.1
1,893,478 - +0.0
1,893,525 + +1.2
1,893,571 - -0.8
1,893,571 - -0.3
1,893,571 - +1.0
1,893,646 + Rv1667c 0.11 +0.9
1,893,646 + Rv1667c 0.11 -0.4
1,893,646 + Rv1667c 0.11 -0.9
1,893,646 + Rv1667c 0.11 -0.2
1,893,646 + Rv1667c 0.11 -0.5
1,893,646 + Rv1667c 0.11 -0.6
1,893,646 + Rv1667c 0.11 +0.7
1,893,647 - Rv1667c 0.11 -0.8
1,893,647 - Rv1667c 0.11 -0.1
1,893,647 - Rv1667c 0.11 +1.1
1,893,647 - Rv1667c 0.11 -0.6
1,893,647 - Rv1667c 0.11 -1.0
1,893,708 + Rv1667c 0.20 +0.7
1,893,864 - Rv1667c 0.44 -0.3
1,893,914 + Rv1667c 0.52 -0.6
1,893,972 + Rv1667c 0.60 +0.3
1,894,166 - -0.6
1,894,166 - -0.7
1,894,166 - -0.1
1,894,225 + -0.2
1,894,457 - Rv1668c 0.21 -0.2
1,894,457 - Rv1668c 0.21 -1.5

Or see this region's nucleotide sequence