Experiment: pH 5.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1420 and Rv1421 overlap by 4 nucleotides Rv1421 and Rv1422 overlap by 4 nucleotides Rv1422 and Rv1423 overlap by 4 nucleotides Rv1423 and Rv1424c are separated by 9 nucleotides
Rv1420: Rv1420 - Probable excinuclease ABC (subunit C-nuclease) UvrC, at 1,594,042 to 1,595,982
Rv1420
Rv1421: Rv1421 - Conserved protein, at 1,595,979 to 1,596,884
Rv1421
Rv1422: Rv1422 - Conserved hypothetical protein, at 1,596,881 to 1,597,909
Rv1422
Rv1423: Rv1423 - Probable transcriptional regulatory protein WhiA, at 1,597,906 to 1,598,883
Rv1423
Rv1424c: Rv1424c - Possible membrane protein, at 1,598,893 to 1,599,654
Rv1424c
Position (kb)
1596
1597
1598 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1596.105 kb on + strand, within Rv1421 at 1596.400 kb on + strand, within Rv1421 at 1596.710 kb on - strand, within Rv1421 at 1596.753 kb on - strand, within Rv1421 at 1596.783 kb on - strand, within Rv1421 at 1596.960 kb on - strand at 1597.485 kb on + strand, within Rv1422 at 1597.486 kb on - strand, within Rv1422 at 1597.770 kb on + strand, within Rv1422 at 1598.895 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction pH 5.5 remove 1,596,105 + Rv1421 0.14 -1.4 1,596,400 + Rv1421 0.46 -1.6 1,596,710 - Rv1421 0.81 -1.1 1,596,753 - Rv1421 0.85 +0.2 1,596,783 - Rv1421 0.89 +0.3 1,596,960 - +0.3 1,597,485 + Rv1422 0.59 +1.7 1,597,486 - Rv1422 0.59 -2.6 1,597,770 + Rv1422 0.86 -0.4 1,598,895 - +2.1
Or see this region's nucleotide sequence