Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1209

Experiment: pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1208 and Rv1209 are separated by 38 nucleotidesRv1209 and Rv1210 overlap by 4 nucleotidesRv1210 and Rv1211 are separated by 106 nucleotidesRv1211 and Rv1212c are separated by 27 nucleotides Rv1208: Rv1208 - Probable glucosyl-3-phosphoglycerate synthase GpgS, at 1,352,144 to 1,353,118 Rv1208 Rv1209: Rv1209 - Conserved protein, at 1,353,157 to 1,353,525 Rv1209 Rv1210: Rv1210 - Probable DNA-3-methyladenine glycosylase I TagA (tag I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I), at 1,353,522 to 1,354,136 Rv1210 Rv1211: Rv1211 - Conserved protein, at 1,354,243 to 1,354,470 Rv1211 Rv1212c: Rv1212c - Putative glycosyl transferase GlgA, at 1,354,498 to 1,355,661 Rv1212c Position (kb) 1353 1354Strain fitness (log2 ratio) -2 -1 0 1at 1353.139 kb on + strandat 1353.176 kb on - strandat 1353.176 kb on - strandat 1353.352 kb on + strand, within Rv1209at 1353.410 kb on + strand, within Rv1209at 1353.411 kb on - strand, within Rv1209at 1353.411 kb on - strand, within Rv1209at 1353.411 kb on - strand, within Rv1209at 1353.588 kb on + strand, within Rv1210at 1353.588 kb on + strand, within Rv1210at 1353.597 kb on + strand, within Rv1210at 1353.695 kb on - strand, within Rv1210at 1353.763 kb on - strand, within Rv1210at 1353.787 kb on + strand, within Rv1210at 1353.883 kb on + strand, within Rv1210at 1353.883 kb on + strand, within Rv1210at 1353.974 kb on + strand, within Rv1210at 1353.975 kb on - strand, within Rv1210at 1353.975 kb on - strand, within Rv1210at 1354.029 kb on + strand, within Rv1210at 1354.029 kb on + strand, within Rv1210at 1354.068 kb on - strand, within Rv1210at 1354.068 kb on - strand, within Rv1210at 1354.464 kb on + strandat 1354.468 kb on + strandat 1354.469 kb on - strandat 1354.517 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 5.5
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1,353,139 + +0.9
1,353,176 - -0.4
1,353,176 - -0.7
1,353,352 + Rv1209 0.53 -1.7
1,353,410 + Rv1209 0.69 -0.9
1,353,411 - Rv1209 0.69 -0.9
1,353,411 - Rv1209 0.69 -1.4
1,353,411 - Rv1209 0.69 -0.8
1,353,588 + Rv1210 0.11 -1.0
1,353,588 + Rv1210 0.11 -0.1
1,353,597 + Rv1210 0.12 -0.3
1,353,695 - Rv1210 0.28 +1.2
1,353,763 - Rv1210 0.39 -0.7
1,353,787 + Rv1210 0.43 -0.6
1,353,883 + Rv1210 0.59 -0.4
1,353,883 + Rv1210 0.59 +0.3
1,353,974 + Rv1210 0.73 +0.3
1,353,975 - Rv1210 0.74 +0.7
1,353,975 - Rv1210 0.74 -0.0
1,354,029 + Rv1210 0.82 +1.3
1,354,029 + Rv1210 0.82 +0.5
1,354,068 - Rv1210 0.89 +0.4
1,354,068 - Rv1210 0.89 -1.9
1,354,464 + +0.9
1,354,468 + +0.1
1,354,469 - -0.7
1,354,517 + -0.2

Or see this region's nucleotide sequence