Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0373c

Experiment: pH 5.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0371c and Rv0372c overlap by 4 nucleotidesRv0372c and Rv0373c are separated by 18 nucleotidesRv0373c and Rv0374c overlap by 4 nucleotidesRv0374c and Rv0375c are separated by 14 nucleotides Rv0371c: Rv0371c - Conserved hypothetical protein, at 448,040 to 448,633 Rv0371c Rv0372c: Rv0372c - Conserved hypothetical protein, at 448,630 to 449,385 Rv0372c Rv0373c: Rv0373c - Probable carbon monoxyde dehydrogenase (large chain), at 449,404 to 451,803 Rv0373c Rv0374c: Rv0374c - Probable carbon monoxyde dehydrogenase (small chain), at 451,800 to 452,279 Rv0374c Rv0375c: Rv0375c - Probable carbon monoxyde dehydrogenase (medium chain), at 452,294 to 453,154 Rv0375c Position (kb) 449 450 451 452Strain fitness (log2 ratio) -2 -1 0 1at 449.405 kb on + strandat 449.646 kb on - strand, within Rv0373cat 449.862 kb on - strand, within Rv0373cat 449.867 kb on + strand, within Rv0373cat 449.868 kb on - strand, within Rv0373cat 450.140 kb on + strand, within Rv0373cat 450.141 kb on - strand, within Rv0373cat 450.720 kb on - strand, within Rv0373cat 450.738 kb on - strand, within Rv0373cat 450.884 kb on + strand, within Rv0373cat 450.983 kb on + strand, within Rv0373cat 451.199 kb on + strand, within Rv0373cat 451.492 kb on + strand, within Rv0373cat 451.492 kb on + strand, within Rv0373cat 451.864 kb on + strand, within Rv0374cat 451.955 kb on + strand, within Rv0374cat 452.386 kb on - strand, within Rv0375cat 452.386 kb on - strand, within Rv0375c

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 5.5
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449,405 + -0.2
449,646 - Rv0373c 0.10 -0.3
449,862 - Rv0373c 0.19 -2.1
449,867 + Rv0373c 0.19 -0.3
449,868 - Rv0373c 0.19 -1.1
450,140 + Rv0373c 0.31 -1.2
450,141 - Rv0373c 0.31 -0.4
450,720 - Rv0373c 0.55 +0.4
450,738 - Rv0373c 0.56 +0.2
450,884 + Rv0373c 0.62 -2.2
450,983 + Rv0373c 0.66 -0.5
451,199 + Rv0373c 0.75 -0.5
451,492 + Rv0373c 0.87 +0.6
451,492 + Rv0373c 0.87 -0.2
451,864 + Rv0374c 0.13 -0.7
451,955 + Rv0374c 0.32 -0.5
452,386 - Rv0375c 0.11 +0.1
452,386 - Rv0375c 0.11 +0.4

Or see this region's nucleotide sequence