Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0256c

Experiment: pH 4.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0255c and Rv0256c are separated by 18 nucleotidesRv0256c and Rv0257 are separated by 151 nucleotidesRv0257 and Rv0258c are separated by 220 nucleotides Rv0255c: Rv0255c - Probable cobyric acid synthase CobQ1, at 306,374 to 307,858 Rv0255c Rv0256c: Rv0256c - PPE family protein PPE2, at 307,877 to 309,547 Rv0256c Rv0257: Rv0257 - Conserved hypothetical protein, at 309,699 to 310,073 Rv0257 Rv0258c: Rv0258c - Conserved hypothetical protein, at 310,294 to 310,749 Rv0258c Position (kb) 307 308 309 310Strain fitness (log2 ratio) -1 0 1 2at 306.911 kb on + strand, within Rv0255cat 306.912 kb on - strand, within Rv0255cat 307.131 kb on - strand, within Rv0255cat 307.188 kb on + strand, within Rv0255cat 307.189 kb on - strand, within Rv0255cat 307.189 kb on - strand, within Rv0255cat 307.261 kb on + strand, within Rv0255cat 307.750 kb on + strandat 307.816 kb on + strandat 307.817 kb on - strandat 308.075 kb on + strand, within Rv0256cat 308.268 kb on + strand, within Rv0256cat 308.268 kb on + strand, within Rv0256cat 308.283 kb on - strand, within Rv0256cat 308.283 kb on - strand, within Rv0256cat 308.674 kb on + strand, within Rv0256cat 308.754 kb on + strand, within Rv0256cat 308.754 kb on + strand, within Rv0256cat 308.754 kb on + strand, within Rv0256cat 308.754 kb on + strand, within Rv0256cat 308.754 kb on + strand, within Rv0256cat 308.755 kb on - strand, within Rv0256cat 308.755 kb on - strand, within Rv0256cat 308.755 kb on - strand, within Rv0256cat 308.816 kb on + strand, within Rv0256cat 308.910 kb on - strand, within Rv0256cat 308.910 kb on - strand, within Rv0256cat 308.910 kb on - strand, within Rv0256cat 308.923 kb on - strand, within Rv0256cat 308.923 kb on - strand, within Rv0256cat 309.078 kb on + strand, within Rv0256cat 309.079 kb on - strand, within Rv0256cat 309.079 kb on - strand, within Rv0256cat 309.331 kb on + strand, within Rv0256cat 309.331 kb on + strand, within Rv0256cat 309.332 kb on - strand, within Rv0256cat 309.332 kb on - strand, within Rv0256cat 309.345 kb on + strand, within Rv0256cat 309.345 kb on + strand, within Rv0256cat 309.495 kb on - strandat 309.598 kb on - strandat 309.631 kb on - strandat 309.631 kb on - strandat 309.763 kb on + strand, within Rv0257at 309.763 kb on + strand, within Rv0257at 309.763 kb on + strand, within Rv0257at 309.764 kb on - strand, within Rv0257at 309.849 kb on - strand, within Rv0257at 310.237 kb on - strandat 310.237 kb on - strandat 310.284 kb on - strandat 310.400 kb on + strand, within Rv0258c

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 4.5
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306,911 + Rv0255c 0.36 -0.3
306,912 - Rv0255c 0.36 +0.6
307,131 - Rv0255c 0.51 +0.0
307,188 + Rv0255c 0.55 +1.2
307,189 - Rv0255c 0.55 +0.8
307,189 - Rv0255c 0.55 -0.6
307,261 + Rv0255c 0.60 -0.3
307,750 + -0.8
307,816 + -0.6
307,817 - -1.2
308,075 + Rv0256c 0.12 -0.7
308,268 + Rv0256c 0.23 -0.5
308,268 + Rv0256c 0.23 -0.1
308,283 - Rv0256c 0.24 +0.5
308,283 - Rv0256c 0.24 +0.1
308,674 + Rv0256c 0.48 -0.1
308,754 + Rv0256c 0.52 +0.2
308,754 + Rv0256c 0.52 -0.9
308,754 + Rv0256c 0.52 -0.3
308,754 + Rv0256c 0.52 -0.9
308,754 + Rv0256c 0.52 -1.1
308,755 - Rv0256c 0.53 +1.1
308,755 - Rv0256c 0.53 +0.4
308,755 - Rv0256c 0.53 +0.8
308,816 + Rv0256c 0.56 -0.9
308,910 - Rv0256c 0.62 -0.2
308,910 - Rv0256c 0.62 +0.0
308,910 - Rv0256c 0.62 -0.2
308,923 - Rv0256c 0.63 +0.8
308,923 - Rv0256c 0.63 +1.0
309,078 + Rv0256c 0.72 +0.2
309,079 - Rv0256c 0.72 +1.9
309,079 - Rv0256c 0.72 -0.5
309,331 + Rv0256c 0.87 +0.5
309,331 + Rv0256c 0.87 +2.5
309,332 - Rv0256c 0.87 -0.4
309,332 - Rv0256c 0.87 +0.1
309,345 + Rv0256c 0.88 -1.4
309,345 + Rv0256c 0.88 -0.8
309,495 - +0.3
309,598 - -0.1
309,631 - -1.5
309,631 - +0.3
309,763 + Rv0257 0.17 +0.4
309,763 + Rv0257 0.17 +0.2
309,763 + Rv0257 0.17 -0.5
309,764 - Rv0257 0.17 +0.2
309,849 - Rv0257 0.40 +0.4
310,237 - -0.6
310,237 - -0.6
310,284 - -0.8
310,400 + Rv0258c 0.23 -0.2

Or see this region's nucleotide sequence