Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3476c

Experiment: pH 4.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3475 and Rv3476c are separated by 279 nucleotidesRv3476c and Rv3477 are separated by 372 nucleotidesRv3477 and Rv3478 are separated by 36 nucleotides Rv3475: Rv3475 - Possible transposase for insertion element IS6110 [second part], at 3,891,105 to 3,892,091 Rv3475 Rv3476c: Rv3476c - Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter), at 3,892,371 to 3,893,720 Rv3476c Rv3477: Rv3477 - PE family protein PE31, at 3,894,093 to 3,894,389 Rv3477 Rv3478: Rv3478 - PE family protein PPE60, at 3,894,426 to 3,895,607 Rv3478 Position (kb) 3892 3893 3894Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3892.223 kb on + strandat 3892.223 kb on + strandat 3892.224 kb on - strandat 3892.356 kb on - strandat 3892.356 kb on - strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.372 kb on + strandat 3892.414 kb on + strandat 3892.414 kb on + strandat 3892.414 kb on + strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.415 kb on - strandat 3892.418 kb on + strandat 3892.447 kb on + strandat 3892.448 kb on - strandat 3892.517 kb on + strand, within Rv3476cat 3892.528 kb on + strand, within Rv3476cat 3892.720 kb on + strand, within Rv3476cat 3892.735 kb on + strand, within Rv3476cat 3892.736 kb on - strand, within Rv3476cat 3892.739 kb on + strand, within Rv3476cat 3892.741 kb on + strand, within Rv3476cat 3892.742 kb on - strand, within Rv3476cat 3892.742 kb on - strand, within Rv3476cat 3892.921 kb on + strand, within Rv3476cat 3892.922 kb on - strand, within Rv3476cat 3892.922 kb on - strand, within Rv3476cat 3892.926 kb on - strand, within Rv3476cat 3893.284 kb on + strand, within Rv3476cat 3893.285 kb on - strand, within Rv3476cat 3893.346 kb on - strand, within Rv3476cat 3893.513 kb on + strand, within Rv3476cat 3893.514 kb on - strand, within Rv3476cat 3893.536 kb on + strand, within Rv3476cat 3893.585 kb on - strand, within Rv3476cat 3893.588 kb on + strandat 3893.608 kb on + strandat 3893.609 kb on - strandat 3893.617 kb on + strandat 3893.617 kb on + strandat 3894.273 kb on + strand, within Rv3477at 3894.348 kb on + strand, within Rv3477

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 4.5
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3,892,223 + -0.3
3,892,223 + +0.5
3,892,224 - +0.8
3,892,356 - -0.5
3,892,356 - +0.3
3,892,372 + +0.7
3,892,372 + -0.2
3,892,372 + -0.4
3,892,372 + -2.2
3,892,414 + -0.0
3,892,414 + -0.1
3,892,414 + -0.5
3,892,415 - -0.5
3,892,415 - -1.5
3,892,415 - -0.8
3,892,415 - +0.6
3,892,418 + -0.2
3,892,447 + +0.2
3,892,448 - +1.0
3,892,517 + Rv3476c 0.11 +1.8
3,892,528 + Rv3476c 0.12 -3.3
3,892,720 + Rv3476c 0.26 -0.4
3,892,735 + Rv3476c 0.27 -0.0
3,892,736 - Rv3476c 0.27 +1.8
3,892,739 + Rv3476c 0.27 -0.1
3,892,741 + Rv3476c 0.27 -0.2
3,892,742 - Rv3476c 0.27 -1.1
3,892,742 - Rv3476c 0.27 -1.1
3,892,921 + Rv3476c 0.41 -1.3
3,892,922 - Rv3476c 0.41 -0.7
3,892,922 - Rv3476c 0.41 -1.3
3,892,926 - Rv3476c 0.41 +0.1
3,893,284 + Rv3476c 0.68 -0.5
3,893,285 - Rv3476c 0.68 -1.2
3,893,346 - Rv3476c 0.72 -0.3
3,893,513 + Rv3476c 0.85 -1.3
3,893,514 - Rv3476c 0.85 -0.1
3,893,536 + Rv3476c 0.86 +0.3
3,893,585 - Rv3476c 0.90 +0.6
3,893,588 + -0.6
3,893,608 + -0.9
3,893,609 - +0.4
3,893,617 + -1.7
3,893,617 + +0.7
3,894,273 + Rv3477 0.61 +0.5
3,894,348 + Rv3477 0.86 -1.3

Or see this region's nucleotide sequence