Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2718c

Experiment: pH 4.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2716 and Rv2717c are separated by 8 nucleotidesRv2717c and Rv2718c are separated by 51 nucleotidesRv2718c and Rv2719c are separated by 162 nucleotidesRv2719c and Rv2720 are separated by 250 nucleotides Rv2716: Rv2716 - Conserved protein, at 3,029,172 to 3,029,858 Rv2716 Rv2717c: Rv2717c - Conserved protein, at 3,029,867 to 3,030,361 Rv2717c Rv2718c: Rv2718c - Probable transcriptional regulatory protein NrdR, at 3,030,413 to 3,030,877 Rv2718c Rv2719c: Rv2719c - Possible conserved membrane protein, at 3,031,040 to 3,031,537 Rv2719c Rv2720: Rv2720 - Repressor LexA, at 3,031,788 to 3,032,498 Rv2720 Position (kb) 3030 3031Strain fitness (log2 ratio) -1 0 1 2at 3029.448 kb on - strand, within Rv2716at 3029.448 kb on - strand, within Rv2716at 3029.487 kb on + strand, within Rv2716at 3029.487 kb on + strand, within Rv2716at 3029.616 kb on + strand, within Rv2716at 3029.617 kb on - strand, within Rv2716at 3030.153 kb on + strand, within Rv2717cat 3030.210 kb on + strand, within Rv2717cat 3030.226 kb on + strand, within Rv2717cat 3030.227 kb on - strand, within Rv2717cat 3030.259 kb on - strand, within Rv2717cat 3030.283 kb on - strand, within Rv2717cat 3030.428 kb on + strandat 3030.428 kb on + strandat 3030.512 kb on + strand, within Rv2718cat 3030.512 kb on + strand, within Rv2718cat 3030.512 kb on + strand, within Rv2718cat 3030.513 kb on - strand, within Rv2718cat 3030.513 kb on - strand, within Rv2718cat 3030.517 kb on - strand, within Rv2718cat 3030.735 kb on - strand, within Rv2718cat 3030.929 kb on + strandat 3030.929 kb on + strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3031.193 kb on + strand, within Rv2719cat 3031.300 kb on + strand, within Rv2719cat 3031.301 kb on - strand, within Rv2719cat 3031.398 kb on + strand, within Rv2719cat 3031.513 kb on + strandat 3031.775 kb on + strandat 3031.775 kb on + strandat 3031.775 kb on + strandat 3031.776 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 4.5
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3,029,448 - Rv2716 0.40 +1.8
3,029,448 - Rv2716 0.40 +0.2
3,029,487 + Rv2716 0.46 +0.6
3,029,487 + Rv2716 0.46 -0.9
3,029,616 + Rv2716 0.65 -0.1
3,029,617 - Rv2716 0.65 -0.1
3,030,153 + Rv2717c 0.58 +1.8
3,030,210 + Rv2717c 0.69 +1.8
3,030,226 + Rv2717c 0.73 -0.1
3,030,227 - Rv2717c 0.73 -0.9
3,030,259 - Rv2717c 0.79 -0.6
3,030,283 - Rv2717c 0.84 -0.0
3,030,428 + -0.0
3,030,428 + -0.4
3,030,512 + Rv2718c 0.21 -1.3
3,030,512 + Rv2718c 0.21 +0.2
3,030,512 + Rv2718c 0.21 -0.9
3,030,513 - Rv2718c 0.22 -1.0
3,030,513 - Rv2718c 0.22 -1.3
3,030,517 - Rv2718c 0.22 -0.6
3,030,735 - Rv2718c 0.69 -0.8
3,030,929 + -0.5
3,030,929 + -0.4
3,030,930 - -0.7
3,030,930 - -1.7
3,030,930 - -0.5
3,030,930 - +1.8
3,030,930 - -0.5
3,031,193 + Rv2719c 0.31 -0.1
3,031,300 + Rv2719c 0.52 +0.5
3,031,301 - Rv2719c 0.52 +1.0
3,031,398 + Rv2719c 0.72 +0.0
3,031,513 + +0.8
3,031,775 + +0.3
3,031,775 + +0.9
3,031,775 + -0.1
3,031,776 - +0.8

Or see this region's nucleotide sequence