Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0132c

Experiment: pH 4.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0131c and Rv0132c are separated by 41 nucleotidesRv0132c and Rv0133 are separated by 86 nucleotidesRv0133 and Rv0134 are separated by 296 nucleotides Rv0131c: Rv0131c - Probable acyl-CoA dehydrogenase FadE1, at 158,315 to 159,658 Rv0131c Rv0132c: Rv0132c - Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2, at 159,700 to 160,782 Rv0132c Rv0133: Rv0133 - GCN5-related N-acetyltransferase, at 160,869 to 161,474 Rv0133 Rv0134: Rv0134 - Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase), at 161,771 to 162,673 Rv0134 Position (kb) 159 160 161Strain fitness (log2 ratio) -2 -1 0 1at 158.761 kb on + strand, within Rv0131cat 158.840 kb on + strand, within Rv0131cat 159.045 kb on + strand, within Rv0131cat 159.046 kb on - strand, within Rv0131cat 159.592 kb on - strandat 160.264 kb on + strand, within Rv0132cat 160.264 kb on + strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.265 kb on - strand, within Rv0132cat 160.302 kb on - strand, within Rv0132cat 160.302 kb on - strand, within Rv0132cat 160.427 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.433 kb on + strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.434 kb on - strand, within Rv0132cat 160.436 kb on - strand, within Rv0132cat 160.546 kb on + strand, within Rv0132cat 160.546 kb on + strand, within Rv0132cat 160.547 kb on - strand, within Rv0132cat 160.547 kb on - strand, within Rv0132cat 160.568 kb on + strand, within Rv0132cat 160.569 kb on - strand, within Rv0132cat 160.941 kb on + strand, within Rv0133at 160.941 kb on + strand, within Rv0133at 160.966 kb on + strand, within Rv0133at 160.967 kb on - strand, within Rv0133at 161.245 kb on - strand, within Rv0133at 161.245 kb on - strand, within Rv0133at 161.245 kb on - strand, within Rv0133at 161.349 kb on + strand, within Rv0133at 161.385 kb on + strand, within Rv0133at 161.386 kb on - strand, within Rv0133at 161.386 kb on - strand, within Rv0133at 161.386 kb on - strand, within Rv0133at 161.446 kb on + strandat 161.607 kb on + strandat 161.608 kb on - strandat 161.702 kb on - strandat 161.702 kb on - strandat 161.702 kb on - strandat 161.702 kb on - strandat 161.756 kb on + strandat 161.756 kb on + strandat 161.756 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction pH 4.5
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158,761 + Rv0131c 0.33 +0.3
158,840 + Rv0131c 0.39 -0.1
159,045 + Rv0131c 0.54 -0.4
159,046 - Rv0131c 0.54 +0.6
159,592 - +0.0
160,264 + Rv0132c 0.52 -1.5
160,264 + Rv0132c 0.52 +0.6
160,265 - Rv0132c 0.52 +0.6
160,265 - Rv0132c 0.52 -0.2
160,265 - Rv0132c 0.52 -0.2
160,302 - Rv0132c 0.56 -0.5
160,302 - Rv0132c 0.56 -1.2
160,427 + Rv0132c 0.67 +0.8
160,433 + Rv0132c 0.68 +0.7
160,433 + Rv0132c 0.68 -0.8
160,433 + Rv0132c 0.68 -0.5
160,434 - Rv0132c 0.68 +1.7
160,434 - Rv0132c 0.68 +0.1
160,434 - Rv0132c 0.68 +0.2
160,434 - Rv0132c 0.68 -1.2
160,436 - Rv0132c 0.68 -0.4
160,546 + Rv0132c 0.78 +1.2
160,546 + Rv0132c 0.78 +0.1
160,547 - Rv0132c 0.78 +1.7
160,547 - Rv0132c 0.78 +0.0
160,568 + Rv0132c 0.80 -0.2
160,569 - Rv0132c 0.80 +0.2
160,941 + Rv0133 0.12 +0.2
160,941 + Rv0133 0.12 +0.7
160,966 + Rv0133 0.16 +0.7
160,967 - Rv0133 0.16 -0.8
161,245 - Rv0133 0.62 +0.1
161,245 - Rv0133 0.62 -0.3
161,245 - Rv0133 0.62 -1.4
161,349 + Rv0133 0.79 +0.4
161,385 + Rv0133 0.85 -0.5
161,386 - Rv0133 0.85 +0.4
161,386 - Rv0133 0.85 +1.1
161,386 - Rv0133 0.85 -0.3
161,446 + +1.2
161,607 + -1.9
161,608 - +0.2
161,702 - -0.4
161,702 - -0.2
161,702 - -0.2
161,702 - -0.3
161,756 + +0.2
161,756 + -1.1
161,756 + -0.2

Or see this region's nucleotide sequence