Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2492

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2491 and Rv2492 overlap by 11 nucleotidesRv2492 and Rv2493 are separated by 52 nucleotidesRv2493 and Rv2494 are separated by 5 nucleotidesRv2494 and Rv2495c are separated by 22 nucleotides Rv2491: Rv2491 - Conserved hypothetical protein, at 2,806,665 to 2,807,288 Rv2491 Rv2492: Rv2492 - Hypothetical protein, at 2,807,278 to 2,808,030 Rv2492 Rv2493: Rv2493 - Possible antitoxin VapB38, at 2,808,083 to 2,808,304 Rv2493 Rv2494: Rv2494 - Possible toxin VapC38. Contains PIN domain., at 2,808,310 to 2,808,735 Rv2494 Rv2495c: Rv2495c - Probable branched-chain keto acid dehydrogenase E2 component BkdC, at 2,808,758 to 2,809,939 Rv2495c Position (kb) 2807 2808 2809Strain fitness (log2 ratio) -1 0 1at 2806.288 kb on - strandat 2806.288 kb on - strandat 2806.325 kb on - strandat 2806.325 kb on - strandat 2806.535 kb on + strandat 2806.535 kb on + strandat 2806.535 kb on + strandat 2806.536 kb on - strandat 2806.536 kb on - strandat 2806.536 kb on - strandat 2806.536 kb on - strandat 2806.536 kb on - strandat 2806.554 kb on - strandat 2806.554 kb on - strandat 2806.731 kb on - strand, within Rv2491at 2806.733 kb on + strand, within Rv2491at 2806.734 kb on - strand, within Rv2491at 2806.800 kb on + strand, within Rv2491at 2807.105 kb on - strand, within Rv2491at 2807.331 kb on - strandat 2807.409 kb on - strand, within Rv2492at 2807.492 kb on + strand, within Rv2492at 2807.944 kb on - strand, within Rv2492at 2808.029 kb on - strandat 2808.040 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,806,288 - -0.9
2,806,288 - -0.3
2,806,325 - -0.1
2,806,325 - -0.6
2,806,535 + +1.4
2,806,535 + -1.2
2,806,535 + -0.2
2,806,536 - +0.1
2,806,536 - -0.6
2,806,536 - -0.3
2,806,536 - +0.4
2,806,536 - -0.1
2,806,554 - -0.2
2,806,554 - -0.5
2,806,731 - Rv2491 0.11 -0.1
2,806,733 + Rv2491 0.11 -1.3
2,806,734 - Rv2491 0.11 +0.3
2,806,800 + Rv2491 0.22 -0.8
2,807,105 - Rv2491 0.71 -0.4
2,807,331 - +0.8
2,807,409 - Rv2492 0.17 +0.9
2,807,492 + Rv2492 0.28 -0.2
2,807,944 - Rv2492 0.88 +0.8
2,808,029 - -1.0
2,808,040 + -0.7

Or see this region's nucleotide sequence