Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3622c

Experiment: 7H9 with hypochlorite 0.4 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3621c and Rv3622c are separated by 9 nucleotidesRv3622c and Rv3623 are separated by 328 nucleotides Rv3621c: Rv3621c - PPE family protein PPE65, at 4,060,648 to 4,061,889 Rv3621c Rv3622c: Rv3622c - PE family protein PE32, at 4,061,899 to 4,062,198 Rv3622c Rv3623: Rv3623 - Probable conserved lipoprotein LpqG, at 4,062,527 to 4,063,249 Rv3623 Position (kb) 4061 4062 4063Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 4061.031 kb on - strand, within Rv3621cat 4061.031 kb on - strand, within Rv3621cat 4061.427 kb on - strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.598 kb on - strand, within Rv3621cat 4061.753 kb on + strand, within Rv3621cat 4061.754 kb on - strand, within Rv3621cat 4061.754 kb on - strand, within Rv3621cat 4061.840 kb on + strandat 4061.840 kb on + strandat 4061.840 kb on + strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.939 kb on + strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4062.004 kb on - strand, within Rv3622cat 4062.014 kb on + strand, within Rv3622cat 4062.014 kb on + strand, within Rv3622cat 4062.201 kb on + strandat 4062.201 kb on + strandat 4062.202 kb on - strandat 4062.215 kb on + strandat 4062.233 kb on + strandat 4062.233 kb on + strandat 4062.330 kb on - strandat 4062.514 kb on + strandat 4062.839 kb on + strand, within Rv3623at 4062.839 kb on + strand, within Rv3623at 4062.840 kb on - strand, within Rv3623at 4062.996 kb on - strand, within Rv3623at 4063.077 kb on - strand, within Rv3623at 4063.077 kb on - strand, within Rv3623

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
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4,061,031 - Rv3621c 0.31 +0.2
4,061,031 - Rv3621c 0.31 -1.3
4,061,427 - Rv3621c 0.63 +1.1
4,061,432 + Rv3621c 0.63 -0.1
4,061,432 + Rv3621c 0.63 -1.5
4,061,432 + Rv3621c 0.63 -0.2
4,061,433 - Rv3621c 0.63 +2.3
4,061,433 - Rv3621c 0.63 -0.5
4,061,433 - Rv3621c 0.63 -0.2
4,061,433 - Rv3621c 0.63 +3.4
4,061,433 - Rv3621c 0.63 -0.5
4,061,433 - Rv3621c 0.63 -0.2
4,061,597 + Rv3621c 0.76 +1.1
4,061,597 + Rv3621c 0.76 +0.2
4,061,597 + Rv3621c 0.76 +2.8
4,061,597 + Rv3621c 0.76 -0.1
4,061,598 - Rv3621c 0.76 -0.5
4,061,753 + Rv3621c 0.89 -0.8
4,061,754 - Rv3621c 0.89 -1.6
4,061,754 - Rv3621c 0.89 -2.4
4,061,840 + -0.1
4,061,840 + +0.0
4,061,840 + -0.2
4,061,841 - -0.6
4,061,841 - +0.8
4,061,841 - +0.6
4,061,841 - +0.8
4,061,939 + Rv3622c 0.13 -0.3
4,061,940 - Rv3622c 0.14 -0.3
4,061,940 - Rv3622c 0.14 -1.0
4,061,940 - Rv3622c 0.14 -1.3
4,062,004 - Rv3622c 0.35 -0.5
4,062,014 + Rv3622c 0.38 -1.4
4,062,014 + Rv3622c 0.38 -0.4
4,062,201 + -0.2
4,062,201 + +1.8
4,062,202 - -2.8
4,062,215 + -0.7
4,062,233 + +0.6
4,062,233 + +0.4
4,062,330 - -0.8
4,062,514 + -0.2
4,062,839 + Rv3623 0.43 -0.9
4,062,839 + Rv3623 0.43 -0.8
4,062,840 - Rv3623 0.43 -0.7
4,062,996 - Rv3623 0.65 -0.4
4,063,077 - Rv3623 0.76 -0.3
4,063,077 - Rv3623 0.76 -0.1

Or see this region's nucleotide sequence