Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3813c

Experiment: 7H9 with hypochlorite 0.4 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3812 and Rv3813c are separated by 308 nucleotidesRv3813c and Rv3814c are separated by 14 nucleotidesRv3814c and Rv3815c are separated by 17 nucleotides Rv3812: Rv3812 - PE-PGRS family protein PE_PGRS62, at 4,276,571 to 4,278,085 Rv3812 Rv3813c: Rv3813c - Conserved protein, at 4,278,394 to 4,279,215 Rv3813c Rv3814c: Rv3814c - Possible acyltransferase, at 4,279,230 to 4,280,015 Rv3814c Rv3815c: Rv3815c - Possible acyltransferase, at 4,280,033 to 4,280,788 Rv3815c Position (kb) 4278 4279 4280Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 4277.410 kb on + strand, within Rv3812at 4277.411 kb on - strand, within Rv3812at 4277.492 kb on + strand, within Rv3812at 4277.493 kb on - strand, within Rv3812at 4277.493 kb on - strand, within Rv3812at 4277.660 kb on + strand, within Rv3812at 4277.747 kb on + strand, within Rv3812at 4277.748 kb on - strand, within Rv3812at 4277.752 kb on - strand, within Rv3812at 4277.793 kb on + strand, within Rv3812at 4277.794 kb on - strand, within Rv3812at 4278.041 kb on + strandat 4278.041 kb on + strandat 4278.041 kb on + strandat 4278.042 kb on - strandat 4278.042 kb on - strandat 4278.113 kb on + strandat 4278.114 kb on - strandat 4278.114 kb on - strandat 4278.395 kb on + strandat 4278.663 kb on - strand, within Rv3813cat 4278.735 kb on + strand, within Rv3813cat 4278.821 kb on + strand, within Rv3813cat 4278.822 kb on - strand, within Rv3813cat 4279.108 kb on + strand, within Rv3813cat 4279.109 kb on - strand, within Rv3813cat 4279.396 kb on + strand, within Rv3814cat 4279.407 kb on + strand, within Rv3814cat 4279.407 kb on + strand, within Rv3814cat 4279.584 kb on - strand, within Rv3814cat 4279.658 kb on + strand, within Rv3814cat 4279.675 kb on - strand, within Rv3814cat 4279.778 kb on - strand, within Rv3814cat 4279.791 kb on + strand, within Rv3814cat 4279.792 kb on - strand, within Rv3814cat 4279.876 kb on + strand, within Rv3814cat 4279.877 kb on - strand, within Rv3814cat 4279.877 kb on - strand, within Rv3814cat 4279.877 kb on - strand, within Rv3814cat 4280.017 kb on + strandat 4280.018 kb on - strandat 4280.018 kb on - strandat 4280.018 kb on - strandat 4280.034 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
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4,277,410 + Rv3812 0.55 +0.3
4,277,411 - Rv3812 0.55 +0.0
4,277,492 + Rv3812 0.61 -1.0
4,277,493 - Rv3812 0.61 +0.7
4,277,493 - Rv3812 0.61 -1.2
4,277,660 + Rv3812 0.72 +2.8
4,277,747 + Rv3812 0.78 +0.1
4,277,748 - Rv3812 0.78 +0.0
4,277,752 - Rv3812 0.78 +1.3
4,277,793 + Rv3812 0.81 -0.5
4,277,794 - Rv3812 0.81 +0.3
4,278,041 + -3.1
4,278,041 + -0.6
4,278,041 + -0.6
4,278,042 - +1.4
4,278,042 - -0.1
4,278,113 + +0.5
4,278,114 - +0.0
4,278,114 - -0.2
4,278,395 + +1.8
4,278,663 - Rv3813c 0.33 +2.8
4,278,735 + Rv3813c 0.41 -1.1
4,278,821 + Rv3813c 0.52 -2.8
4,278,822 - Rv3813c 0.52 +1.8
4,279,108 + Rv3813c 0.87 -0.4
4,279,109 - Rv3813c 0.87 +0.8
4,279,396 + Rv3814c 0.21 -0.2
4,279,407 + Rv3814c 0.23 +0.0
4,279,407 + Rv3814c 0.23 +1.3
4,279,584 - Rv3814c 0.45 +0.3
4,279,658 + Rv3814c 0.54 +1.0
4,279,675 - Rv3814c 0.57 -0.2
4,279,778 - Rv3814c 0.70 -0.8
4,279,791 + Rv3814c 0.71 -3.4
4,279,792 - Rv3814c 0.72 +0.1
4,279,876 + Rv3814c 0.82 -0.2
4,279,877 - Rv3814c 0.82 -0.9
4,279,877 - Rv3814c 0.82 -0.5
4,279,877 - Rv3814c 0.82 -0.1
4,280,017 + +1.7
4,280,018 - -1.2
4,280,018 - -0.8
4,280,018 - +2.4
4,280,034 + -0.3

Or see this region's nucleotide sequence