Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3703c

Experiment: 7H9 with hypochlorite 0.4 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3701c and Rv3702c overlap by 4 nucleotidesRv3702c and Rv3703c overlap by 1 nucleotidesRv3703c and Rv3704c overlap by 4 nucleotides Rv3701c: Rv3701c - Conserved hypothetical protein, at 4,143,951 to 4,144,916 Rv3701c Rv3702c: Rv3702c - Conserved hypothetical protein, at 4,144,913 to 4,145,614 Rv3702c Rv3703c: Rv3703c - Conserved hypothetical protein, at 4,145,614 to 4,146,891 Rv3703c Rv3704c: Rv3704c - Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) (GCS) (gamma-glutamyl-L-cysteine synthetase), at 4,146,888 to 4,148,186 Rv3704c Position (kb) 4145 4146 4147Strain fitness (log2 ratio) -1 0 1at 4145.019 kb on + strand, within Rv3702cat 4145.527 kb on - strand, within Rv3702cat 4145.774 kb on + strand, within Rv3703cat 4145.774 kb on + strand, within Rv3703cat 4145.775 kb on - strand, within Rv3703cat 4145.927 kb on + strand, within Rv3703cat 4145.927 kb on + strand, within Rv3703cat 4145.928 kb on - strand, within Rv3703cat 4145.928 kb on - strand, within Rv3703cat 4146.069 kb on - strand, within Rv3703cat 4146.225 kb on - strand, within Rv3703cat 4146.225 kb on - strand, within Rv3703cat 4146.463 kb on + strand, within Rv3703cat 4146.464 kb on - strand, within Rv3703cat 4146.596 kb on + strand, within Rv3703cat 4146.668 kb on + strand, within Rv3703cat 4146.669 kb on - strand, within Rv3703cat 4146.669 kb on - strand, within Rv3703cat 4147.366 kb on + strand, within Rv3704cat 4147.435 kb on + strand, within Rv3704cat 4147.435 kb on + strand, within Rv3704cat 4147.436 kb on - strand, within Rv3704cat 4147.436 kb on - strand, within Rv3704cat 4147.439 kb on + strand, within Rv3704cat 4147.440 kb on - strand, within Rv3704cat 4147.440 kb on - strand, within Rv3704cat 4147.440 kb on - strand, within Rv3704c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
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4,145,019 + Rv3702c 0.15 -0.6
4,145,527 - Rv3702c 0.87 -1.7
4,145,774 + Rv3703c 0.13 -0.7
4,145,774 + Rv3703c 0.13 +1.2
4,145,775 - Rv3703c 0.13 -1.6
4,145,927 + Rv3703c 0.24 -0.8
4,145,927 + Rv3703c 0.24 -0.4
4,145,928 - Rv3703c 0.25 -0.3
4,145,928 - Rv3703c 0.25 -0.7
4,146,069 - Rv3703c 0.36 -1.0
4,146,225 - Rv3703c 0.48 -1.2
4,146,225 - Rv3703c 0.48 -0.7
4,146,463 + Rv3703c 0.66 -0.3
4,146,464 - Rv3703c 0.67 -0.8
4,146,596 + Rv3703c 0.77 -0.2
4,146,668 + Rv3703c 0.82 -0.6
4,146,669 - Rv3703c 0.83 -0.2
4,146,669 - Rv3703c 0.83 -1.3
4,147,366 + Rv3704c 0.37 -1.0
4,147,435 + Rv3704c 0.42 -1.1
4,147,435 + Rv3704c 0.42 -0.6
4,147,436 - Rv3704c 0.42 -1.2
4,147,436 - Rv3704c 0.42 -1.1
4,147,439 + Rv3704c 0.42 -0.5
4,147,440 - Rv3704c 0.42 +0.1
4,147,440 - Rv3704c 0.42 -0.9
4,147,440 - Rv3704c 0.42 -0.5

Or see this region's nucleotide sequence