Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3614c

Experiment: 7H9 with hypochlorite 0.4 vol%

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3611 and Rv3612c overlap by 86 nucleotidesRv3612c and Rv3613c are separated by 33 nucleotidesRv3613c and Rv3614c are separated by 99 nucleotidesRv3614c and Rv3615c are separated by 115 nucleotidesRv3615c and Rv3616c are separated by 73 nucleotides Rv3611: Rv3611 - Hypothetical arginine and proline rich protein, at 4,052,950 to 4,053,603 Rv3611 Rv3612c: Rv3612c - Conserved hypothetical protein, at 4,053,518 to 4,053,847 Rv3612c Rv3613c: Rv3613c - Hypothetical protein, at 4,053,881 to 4,054,042 Rv3613c Rv3614c: Rv3614c - ESX-1 secretion-associated protein EspD, at 4,054,142 to 4,054,696 Rv3614c Rv3615c: Rv3615c - ESX-1 secretion-associated protein EspC, at 4,054,812 to 4,055,123 Rv3615c Rv3616c: Rv3616c - ESX-1 secretion-associated protein A, EspA, at 4,055,197 to 4,056,375 Rv3616c Position (kb) 4054 4055Strain fitness (log2 ratio) -2 -1 0 1 2at 4053.828 kb on + strandat 4053.883 kb on - strandat 4054.058 kb on + strandat 4054.058 kb on + strandat 4054.059 kb on - strandat 4054.061 kb on + strandat 4054.061 kb on + strandat 4054.062 kb on - strandat 4054.062 kb on - strandat 4054.241 kb on + strand, within Rv3614cat 4054.267 kb on + strand, within Rv3614cat 4054.267 kb on + strand, within Rv3614cat 4054.268 kb on - strand, within Rv3614cat 4054.271 kb on + strand, within Rv3614cat 4054.272 kb on - strand, within Rv3614cat 4054.272 kb on - strand, within Rv3614cat 4054.335 kb on + strand, within Rv3614cat 4054.600 kb on + strand, within Rv3614cat 4054.818 kb on - strandat 4054.818 kb on - strandat 4054.862 kb on + strand, within Rv3615cat 4054.863 kb on - strand, within Rv3615cat 4054.865 kb on - strand, within Rv3615cat 4054.866 kb on + strand, within Rv3615cat 4054.866 kb on + strand, within Rv3615cat 4054.867 kb on - strand, within Rv3615cat 4054.867 kb on - strand, within Rv3615cat 4054.951 kb on + strand, within Rv3615cat 4054.951 kb on + strand, within Rv3615cat 4054.951 kb on + strand, within Rv3615cat 4054.959 kb on + strand, within Rv3615cat 4054.960 kb on - strand, within Rv3615cat 4054.960 kb on - strand, within Rv3615cat 4054.960 kb on - strand, within Rv3615cat 4055.082 kb on + strand, within Rv3615cat 4055.083 kb on - strand, within Rv3615cat 4055.083 kb on - strand, within Rv3615cat 4055.143 kb on + strandat 4055.144 kb on - strandat 4055.297 kb on + strandat 4055.371 kb on - strand, within Rv3616c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
remove
4,053,828 + -0.2
4,053,883 - -0.2
4,054,058 + +1.8
4,054,058 + -0.3
4,054,059 - -0.0
4,054,061 + -2.0
4,054,061 + -1.4
4,054,062 - -0.1
4,054,062 - -0.5
4,054,241 + Rv3614c 0.18 -0.2
4,054,267 + Rv3614c 0.23 -2.6
4,054,267 + Rv3614c 0.23 -0.7
4,054,268 - Rv3614c 0.23 +0.3
4,054,271 + Rv3614c 0.23 -1.6
4,054,272 - Rv3614c 0.23 -0.6
4,054,272 - Rv3614c 0.23 -2.2
4,054,335 + Rv3614c 0.35 -0.9
4,054,600 + Rv3614c 0.83 +1.8
4,054,818 - -0.7
4,054,818 - -0.8
4,054,862 + Rv3615c 0.16 +0.2
4,054,863 - Rv3615c 0.16 -0.0
4,054,865 - Rv3615c 0.17 -0.2
4,054,866 + Rv3615c 0.17 -2.7
4,054,866 + Rv3615c 0.17 -1.0
4,054,867 - Rv3615c 0.18 -1.4
4,054,867 - Rv3615c 0.18 -1.1
4,054,951 + Rv3615c 0.45 +0.2
4,054,951 + Rv3615c 0.45 -0.9
4,054,951 + Rv3615c 0.45 -0.2
4,054,959 + Rv3615c 0.47 -0.9
4,054,960 - Rv3615c 0.47 +0.0
4,054,960 - Rv3615c 0.47 +0.4
4,054,960 - Rv3615c 0.47 +0.0
4,055,082 + Rv3615c 0.87 -0.3
4,055,083 - Rv3615c 0.87 -0.7
4,055,083 - Rv3615c 0.87 -0.2
4,055,143 + -2.4
4,055,144 - -0.4
4,055,297 + +0.1
4,055,371 - Rv3616c 0.15 +1.0

Or see this region's nucleotide sequence