Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3222c

Experiment: 7H9 with hypochlorite 0.4 vol%

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3220c and Rv3221c are separated by 16 nucleotidesRv3221c and Rv3221A are separated by 284 nucleotidesRv3221A and Rv3222c overlap by 4 nucleotidesRv3222c and Rv3223c overlap by 4 nucleotidesRv3223c and Rv3224 are separated by 299 nucleotides Rv3220c: Rv3220c - Probable two component sensor kinase, at 3,596,029 to 3,597,534 Rv3220c Rv3221c: Rv3221c - Biotinylated protein TB7.3, at 3,597,551 to 3,597,766 Rv3221c Rv3221A: Rv3221A - Anti-sigma factor RshA, at 3,598,051 to 3,598,356 Rv3221A Rv3222c: Rv3222c - Conserved hypothetical protein, at 3,598,353 to 3,598,904 Rv3222c Rv3223c: Rv3223c - Alternative RNA polymerase sigma-E factor (sigma-24) SigH (RPOE), at 3,598,901 to 3,599,551 Rv3223c Rv3224: Rv3224 - Possible iron-regulated short-chain dehydrogenase/reductase, at 3,599,851 to 3,600,699 Rv3224 Position (kb) 3598 3599Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3597.416 kb on + strandat 3597.552 kb on + strandat 3597.838 kb on - strandat 3597.838 kb on - strandat 3597.838 kb on - strandat 3597.847 kb on + strandat 3597.847 kb on + strandat 3597.848 kb on - strandat 3597.848 kb on - strandat 3597.848 kb on - strandat 3597.877 kb on + strandat 3597.985 kb on - strandat 3598.003 kb on + strandat 3598.003 kb on + strandat 3598.003 kb on + strandat 3598.039 kb on + strandat 3598.789 kb on - strand, within Rv3222cat 3598.789 kb on - strand, within Rv3222cat 3599.082 kb on + strand, within Rv3223cat 3599.083 kb on - strand, within Rv3223cat 3599.153 kb on + strand, within Rv3223cat 3599.271 kb on + strand, within Rv3223cat 3599.283 kb on + strand, within Rv3223cat 3599.284 kb on - strand, within Rv3223cat 3599.284 kb on - strand, within Rv3223cat 3599.356 kb on - strand, within Rv3223cat 3599.356 kb on - strand, within Rv3223cat 3599.431 kb on - strand, within Rv3223cat 3599.431 kb on - strand, within Rv3223cat 3599.559 kb on - strandat 3599.559 kb on - strandat 3599.690 kb on + strandat 3599.690 kb on + strandat 3599.691 kb on - strandat 3599.691 kb on - strandat 3599.691 kb on - strandat 3599.778 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
remove
3,597,416 + -1.0
3,597,552 + +1.8
3,597,838 - -1.3
3,597,838 - +1.8
3,597,838 - +0.0
3,597,847 + -1.8
3,597,847 + -1.9
3,597,848 - +1.8
3,597,848 - -0.4
3,597,848 - -0.2
3,597,877 + -1.1
3,597,985 - -0.4
3,598,003 + -0.1
3,598,003 + +1.0
3,598,003 + -0.7
3,598,039 + -0.5
3,598,789 - Rv3222c 0.79 -1.5
3,598,789 - Rv3222c 0.79 -3.3
3,599,082 + Rv3223c 0.28 -1.8
3,599,083 - Rv3223c 0.28 +1.8
3,599,153 + Rv3223c 0.39 -1.8
3,599,271 + Rv3223c 0.57 +0.4
3,599,283 + Rv3223c 0.59 +0.6
3,599,284 - Rv3223c 0.59 -0.5
3,599,284 - Rv3223c 0.59 +1.1
3,599,356 - Rv3223c 0.70 +1.0
3,599,356 - Rv3223c 0.70 -2.8
3,599,431 - Rv3223c 0.81 +1.8
3,599,431 - Rv3223c 0.81 +0.7
3,599,559 - -0.5
3,599,559 - +0.6
3,599,690 + -1.1
3,599,690 + -0.2
3,599,691 - -3.4
3,599,691 - -0.5
3,599,691 - -1.0
3,599,778 + -1.4

Or see this region's nucleotide sequence