Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0106

Experiment: 7H9 with hypochlorite 0.4 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0104 and Rv0105c are separated by 148 nucleotidesRv0105c and Rv0106 are separated by 109 nucleotidesRv0106 and Rv0107c are separated by 72 nucleotides Rv0104: Rv0104 - Conserved hypothetical protein, at 122,317 to 123,831 Rv0104 Rv0105c: Rv0105c - 50S ribosomal protein L28-1 RpmB1, at 123,980 to 124,264 Rv0105c Rv0106: Rv0106 - Conserved hypothetical protein, at 124,374 to 125,570 Rv0106 Rv0107c: Rv0107c - Probable cation-transporter ATPase I CtpI, at 125,643 to 130,541 Rv0107c Position (kb) 124 125 126Strain fitness (log2 ratio) -2 -1 0 1 2at 123.521 kb on - strand, within Rv0104at 123.522 kb on + strand, within Rv0104at 123.612 kb on + strand, within Rv0104at 123.830 kb on - strandat 123.896 kb on + strandat 123.896 kb on + strandat 123.906 kb on + strandat 123.906 kb on + strandat 123.910 kb on + strandat 123.910 kb on + strandat 123.910 kb on + strandat 123.911 kb on - strandat 123.911 kb on - strandat 123.911 kb on - strandat 123.911 kb on - strandat 123.911 kb on - strandat 124.379 kb on + strandat 124.390 kb on + strandat 124.391 kb on - strandat 125.015 kb on + strand, within Rv0106at 125.293 kb on - strand, within Rv0106at 125.293 kb on - strand, within Rv0106at 125.293 kb on - strand, within Rv0106at 125.377 kb on + strand, within Rv0106at 125.470 kb on - strandat 125.605 kb on + strandat 125.606 kb on - strandat 125.620 kb on + strandat 125.644 kb on + strandat 125.666 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
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123,521 - Rv0104 0.79 -0.4
123,522 + Rv0104 0.80 -0.7
123,612 + Rv0104 0.85 -1.2
123,830 - +0.3
123,896 + +1.9
123,896 + +0.5
123,906 + +0.2
123,906 + -1.1
123,910 + -0.3
123,910 + -0.7
123,910 + -1.1
123,911 - -0.2
123,911 - -0.4
123,911 - -0.1
123,911 - -0.3
123,911 - -0.7
124,379 + -0.6
124,390 + +0.1
124,391 - +1.9
125,015 + Rv0106 0.54 -0.9
125,293 - Rv0106 0.77 -2.2
125,293 - Rv0106 0.77 +0.3
125,293 - Rv0106 0.77 -0.3
125,377 + Rv0106 0.84 -0.4
125,470 - +0.0
125,605 + -0.3
125,606 - +0.0
125,620 + -0.2
125,644 + -1.7
125,666 + -0.6

Or see this region's nucleotide sequence