Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1357c

Experiment: 7H9 with Nickel (II) chloride 0.6 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1356c and Rv1357c are separated by 472 nucleotidesRv1357c and Rv1358 are separated by 395 nucleotides Rv1356c: Rv1356c - Hypothetical protein, at 1,524,029 to 1,524,820 Rv1356c Rv1357c: Rv1357c - Conserved hypothetical protein, at 1,525,293 to 1,526,216 Rv1357c Rv1358: Rv1358 - Probable transcriptional regulatory protein, at 1,526,612 to 1,530,091 Rv1358 Position (kb) 1525 1526 1527Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1524.370 kb on + strand, within Rv1356cat 1524.625 kb on - strand, within Rv1356cat 1524.649 kb on - strand, within Rv1356cat 1524.653 kb on - strand, within Rv1356cat 1524.686 kb on + strand, within Rv1356cat 1524.687 kb on - strand, within Rv1356cat 1524.838 kb on + strandat 1525.237 kb on + strandat 1525.237 kb on + strandat 1525.238 kb on - strandat 1525.352 kb on + strandat 1525.552 kb on + strand, within Rv1357cat 1525.912 kb on - strand, within Rv1357cat 1525.912 kb on - strand, within Rv1357cat 1525.996 kb on + strand, within Rv1357cat 1526.106 kb on + strand, within Rv1357cat 1526.107 kb on - strand, within Rv1357cat 1526.149 kb on + strandat 1526.356 kb on + strandat 1526.363 kb on + strandat 1526.378 kb on + strandat 1526.378 kb on + strandat 1526.379 kb on - strandat 1526.385 kb on + strandat 1526.385 kb on + strandat 1526.385 kb on + strandat 1526.386 kb on - strandat 1526.386 kb on - strandat 1526.593 kb on + strandat 1526.755 kb on + strandat 1526.827 kb on - strandat 1526.922 kb on + strandat 1526.923 kb on - strandat 1526.923 kb on - strandat 1526.956 kb on - strandat 1526.956 kb on - strandat 1527.013 kb on + strand, within Rv1358

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Nickel (II) chloride 0.6 mM
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1,524,370 + Rv1356c 0.43 +1.9
1,524,625 - Rv1356c 0.75 -0.0
1,524,649 - Rv1356c 0.78 +2.0
1,524,653 - Rv1356c 0.79 -0.0
1,524,686 + Rv1356c 0.83 +0.1
1,524,687 - Rv1356c 0.83 +0.5
1,524,838 + +0.0
1,525,237 + -0.5
1,525,237 + -1.5
1,525,238 - -1.8
1,525,352 + +0.4
1,525,552 + Rv1357c 0.28 -0.5
1,525,912 - Rv1357c 0.67 -0.1
1,525,912 - Rv1357c 0.67 +1.4
1,525,996 + Rv1357c 0.76 +0.1
1,526,106 + Rv1357c 0.88 +1.4
1,526,107 - Rv1357c 0.88 +1.9
1,526,149 + +0.3
1,526,356 + +0.2
1,526,363 + +0.1
1,526,378 + +3.4
1,526,378 + -0.4
1,526,379 - -0.5
1,526,385 + -0.5
1,526,385 + -0.5
1,526,385 + +0.5
1,526,386 - -0.0
1,526,386 - -0.3
1,526,593 + +0.4
1,526,755 + -0.3
1,526,827 - -0.1
1,526,922 + +0.1
1,526,923 - +1.3
1,526,923 - -1.5
1,526,956 - -0.8
1,526,956 - +0.1
1,527,013 + Rv1358 0.12 -0.3

Or see this region's nucleotide sequence