Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3594

Experiment: 7H9 with Geneticin G418 0.35 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3593 and Rv3594 are separated by 146 nucleotidesRv3594 and Rv3595c are separated by 46 nucleotides Rv3593: Rv3593 - Probable conserved lipoprotein LpqF, at 4,034,352 to 4,035,710 Rv3593 Rv3594: Rv3594 - Conserved hypothetical protein, at 4,035,857 to 4,036,684 Rv3594 Rv3595c: Rv3595c - PE-PGRS family protein PE_PGRS59, at 4,036,731 to 4,038,050 Rv3595c Position (kb) 4035 4036 4037Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 4035.708 kb on + strandat 4035.708 kb on + strandat 4035.709 kb on - strandat 4035.709 kb on - strandat 4035.709 kb on - strandat 4035.897 kb on + strandat 4036.092 kb on + strand, within Rv3594at 4036.337 kb on + strand, within Rv3594at 4036.337 kb on + strand, within Rv3594at 4036.338 kb on - strand, within Rv3594at 4036.539 kb on + strand, within Rv3594at 4036.539 kb on + strand, within Rv3594at 4036.540 kb on - strand, within Rv3594at 4036.540 kb on - strand, within Rv3594at 4036.615 kb on + strandat 4036.616 kb on - strandat 4036.616 kb on - strandat 4036.872 kb on - strand, within Rv3595cat 4036.907 kb on + strand, within Rv3595cat 4036.907 kb on + strand, within Rv3595cat 4036.908 kb on - strand, within Rv3595cat 4037.304 kb on - strand, within Rv3595cat 4037.454 kb on - strand, within Rv3595cat 4037.495 kb on - strand, within Rv3595cat 4037.495 kb on - strand, within Rv3595cat 4037.631 kb on - strand, within Rv3595cat 4037.644 kb on + strand, within Rv3595c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Geneticin G418 0.35 mM
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4,035,708 + -0.6
4,035,708 + +0.4
4,035,709 - +0.0
4,035,709 - -0.3
4,035,709 - +0.6
4,035,897 + -0.6
4,036,092 + Rv3594 0.28 +3.1
4,036,337 + Rv3594 0.58 -2.0
4,036,337 + Rv3594 0.58 +0.3
4,036,338 - Rv3594 0.58 -0.3
4,036,539 + Rv3594 0.82 -0.6
4,036,539 + Rv3594 0.82 +4.0
4,036,540 - Rv3594 0.82 -2.1
4,036,540 - Rv3594 0.82 -0.5
4,036,615 + -1.1
4,036,616 - -1.4
4,036,616 - -1.5
4,036,872 - Rv3595c 0.11 -0.1
4,036,907 + Rv3595c 0.13 -0.1
4,036,907 + Rv3595c 0.13 +0.4
4,036,908 - Rv3595c 0.13 -0.4
4,037,304 - Rv3595c 0.43 -0.8
4,037,454 - Rv3595c 0.55 -0.3
4,037,495 - Rv3595c 0.58 +0.3
4,037,495 - Rv3595c 0.58 +1.0
4,037,631 - Rv3595c 0.68 +0.3
4,037,644 + Rv3595c 0.69 +2.0

Or see this region's nucleotide sequence