Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1710

Experiment: 7H9 with Geneticin G418 0.35 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1708 and Rv1709 overlap by 4 nucleotidesRv1709 and Rv1710 overlap by 4 nucleotidesRv1710 and Rv1711 overlap by 4 nucleotidesRv1711 and Rv1712 overlap by 4 nucleotides Rv1708: Rv1708 - Putative initiation inhibitor protein, at 1,936,360 to 1,937,316 Rv1708 Rv1709: Rv1709 - Possible segregation and condensation protein ScpA, at 1,937,313 to 1,938,149 Rv1709 Rv1710: Rv1710 - Possible segregation and condensation protein ScpB, at 1,938,146 to 1,938,841 Rv1710 Rv1711: Rv1711 - Conserved hypothetical protein, at 1,938,838 to 1,939,602 Rv1711 Rv1712: Rv1712 - Cytidylate kinase Cmk (CMP kinase) (cytidine monophosphate kinase) (ck), at 1,939,599 to 1,940,291 Rv1712 Position (kb) 1938 1939Strain fitness (log2 ratio) -2 -1 0 1at 1937.531 kb on - strand, within Rv1709at 1937.645 kb on - strand, within Rv1709at 1937.687 kb on + strand, within Rv1709at 1937.687 kb on + strand, within Rv1709at 1937.740 kb on - strand, within Rv1709at 1937.791 kb on + strand, within Rv1709at 1937.791 kb on + strand, within Rv1709at 1937.792 kb on - strand, within Rv1709at 1937.792 kb on - strand, within Rv1709at 1938.039 kb on + strand, within Rv1709at 1938.056 kb on - strand, within Rv1709at 1938.333 kb on + strand, within Rv1710at 1938.541 kb on + strand, within Rv1710at 1938.580 kb on + strand, within Rv1710at 1939.582 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Geneticin G418 0.35 mM
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1,937,531 - Rv1709 0.26 -1.3
1,937,645 - Rv1709 0.40 -0.5
1,937,687 + Rv1709 0.45 -1.3
1,937,687 + Rv1709 0.45 -0.5
1,937,740 - Rv1709 0.51 -0.4
1,937,791 + Rv1709 0.57 -1.2
1,937,791 + Rv1709 0.57 +0.3
1,937,792 - Rv1709 0.57 +0.6
1,937,792 - Rv1709 0.57 -0.3
1,938,039 + Rv1709 0.87 -1.0
1,938,056 - Rv1709 0.89 +0.9
1,938,333 + Rv1710 0.27 +0.1
1,938,541 + Rv1710 0.57 -2.3
1,938,580 + Rv1710 0.62 -2.0
1,939,582 + -0.1

Or see this region's nucleotide sequence