Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3884c

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3883c and Rv3884c are separated by 221 nucleotidesRv3884c and Rv3885c are separated by 69 nucleotides Rv3883c: Rv3883c - Membrane-anchored mycosin MycP1 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-1), at 4,363,417 to 4,364,757 Rv3883c Rv3884c: Rv3884c - ESX conserved component EccA2. ESX-2 type VII secretion system protein. Probable CbxX/CfqX family protein., at 4,364,979 to 4,366,838 Rv3884c Rv3885c: Rv3885c - ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein., at 4,366,908 to 4,368,521 Rv3885c Position (kb) 4364 4365 4366 4367Strain fitness (log2 ratio) -2 -1 0 1at 4364.029 kb on + strand, within Rv3883cat 4364.144 kb on + strand, within Rv3883cat 4364.145 kb on - strand, within Rv3883cat 4364.305 kb on + strand, within Rv3883cat 4364.305 kb on + strand, within Rv3883cat 4364.552 kb on + strand, within Rv3883cat 4364.552 kb on + strand, within Rv3883cat 4364.748 kb on + strandat 4364.811 kb on + strandat 4364.812 kb on - strandat 4364.812 kb on - strandat 4364.921 kb on + strandat 4365.197 kb on + strand, within Rv3884cat 4365.198 kb on - strand, within Rv3884cat 4365.208 kb on + strand, within Rv3884cat 4365.208 kb on + strand, within Rv3884cat 4365.209 kb on - strand, within Rv3884cat 4365.209 kb on - strand, within Rv3884cat 4365.212 kb on + strand, within Rv3884cat 4365.213 kb on - strand, within Rv3884cat 4365.213 kb on - strand, within Rv3884cat 4365.282 kb on - strand, within Rv3884cat 4365.282 kb on - strand, within Rv3884cat 4365.286 kb on + strand, within Rv3884cat 4365.704 kb on + strand, within Rv3884cat 4365.772 kb on - strand, within Rv3884cat 4366.120 kb on + strand, within Rv3884cat 4366.120 kb on + strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.443 kb on + strand, within Rv3884cat 4366.444 kb on - strand, within Rv3884cat 4366.806 kb on + strandat 4367.473 kb on - strand, within Rv3885cat 4367.740 kb on + strand, within Rv3885c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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4,364,029 + Rv3883c 0.46 +0.1
4,364,144 + Rv3883c 0.54 -0.5
4,364,145 - Rv3883c 0.54 -0.1
4,364,305 + Rv3883c 0.66 -0.5
4,364,305 + Rv3883c 0.66 -0.2
4,364,552 + Rv3883c 0.85 -1.3
4,364,552 + Rv3883c 0.85 +0.9
4,364,748 + -0.2
4,364,811 + +0.1
4,364,812 - -0.2
4,364,812 - +1.7
4,364,921 + -0.1
4,365,197 + Rv3884c 0.12 +0.0
4,365,198 - Rv3884c 0.12 +0.3
4,365,208 + Rv3884c 0.12 -0.2
4,365,208 + Rv3884c 0.12 -0.2
4,365,209 - Rv3884c 0.12 -1.5
4,365,209 - Rv3884c 0.12 -0.4
4,365,212 + Rv3884c 0.13 +0.5
4,365,213 - Rv3884c 0.13 -0.1
4,365,213 - Rv3884c 0.13 +1.7
4,365,282 - Rv3884c 0.16 +0.5
4,365,282 - Rv3884c 0.16 -0.6
4,365,286 + Rv3884c 0.17 -1.0
4,365,704 + Rv3884c 0.39 -1.7
4,365,772 - Rv3884c 0.43 -0.3
4,366,120 + Rv3884c 0.61 +0.3
4,366,120 + Rv3884c 0.61 -2.0
4,366,388 - Rv3884c 0.76 -1.8
4,366,388 - Rv3884c 0.76 -0.6
4,366,388 - Rv3884c 0.76 -1.4
4,366,388 - Rv3884c 0.76 -0.5
4,366,388 - Rv3884c 0.76 -0.7
4,366,424 - Rv3884c 0.78 +0.3
4,366,424 - Rv3884c 0.78 -0.2
4,366,424 - Rv3884c 0.78 -0.6
4,366,443 + Rv3884c 0.79 -1.3
4,366,444 - Rv3884c 0.79 -0.5
4,366,806 + +0.1
4,367,473 - Rv3885c 0.35 -1.0
4,367,740 + Rv3885c 0.52 -0.2

Or see this region's nucleotide sequence