Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3640c

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3638 and Rv3639c are separated by 153 nucleotidesRv3639c and Rv3640c are separated by 69 nucleotidesRv3640c and Rv3641c are separated by 175 nucleotidesRv3641c and Rv3642c are separated by 10 nucleotides Rv3638: Rv3638 - Possible transposase, at 4,076,984 to 4,077,730 Rv3638 Rv3639c: Rv3639c - Conserved hypothetical protein, at 4,077,884 to 4,078,450 Rv3639c Rv3640c: Rv3640c - Probable transposase, at 4,078,520 to 4,079,749 Rv3640c Rv3641c: Rv3641c - Possible cell filamentation protein Fic, at 4,079,925 to 4,080,560 Rv3641c Rv3642c: Rv3642c - Hypothetical protein, at 4,080,571 to 4,080,765 Rv3642c Position (kb) 4078 4079 4080Strain fitness (log2 ratio) -2 -1 0 1 2at 4077.562 kb on + strand, within Rv3638at 4077.588 kb on + strand, within Rv3638at 4077.672 kb on - strandat 4077.790 kb on + strandat 4077.791 kb on - strandat 4077.792 kb on - strandat 4077.939 kb on + strandat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.957 kb on + strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4077.958 kb on - strand, within Rv3639cat 4078.521 kb on + strandat 4078.522 kb on - strandat 4078.583 kb on - strandat 4078.720 kb on + strand, within Rv3640cat 4078.720 kb on + strand, within Rv3640cat 4078.793 kb on + strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.245 kb on - strand, within Rv3640cat 4079.259 kb on + strand, within Rv3640cat 4079.413 kb on + strand, within Rv3640cat 4079.414 kb on - strand, within Rv3640cat 4079.424 kb on + strand, within Rv3640cat 4079.812 kb on - strandat 4079.867 kb on + strandat 4079.917 kb on + strandat 4079.917 kb on + strandat 4079.917 kb on + strandat 4079.935 kb on + strandat 4080.136 kb on + strand, within Rv3641cat 4080.137 kb on - strand, within Rv3641cat 4080.137 kb on - strand, within Rv3641cat 4080.361 kb on + strand, within Rv3641cat 4080.511 kb on + strandat 4080.512 kb on - strandat 4080.512 kb on - strandat 4080.584 kb on + strandat 4080.584 kb on + strandat 4080.585 kb on - strandat 4080.638 kb on + strand, within Rv3642cat 4080.638 kb on + strand, within Rv3642c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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4,077,562 + Rv3638 0.77 -0.1
4,077,588 + Rv3638 0.81 -0.4
4,077,672 - +0.5
4,077,790 + -2.5
4,077,791 - -0.2
4,077,792 - -0.6
4,077,939 + -0.2
4,077,957 + Rv3639c 0.13 -1.2
4,077,957 + Rv3639c 0.13 -1.4
4,077,957 + Rv3639c 0.13 +0.3
4,077,957 + Rv3639c 0.13 +0.2
4,077,958 - Rv3639c 0.13 -0.5
4,077,958 - Rv3639c 0.13 -0.7
4,077,958 - Rv3639c 0.13 +2.6
4,077,958 - Rv3639c 0.13 +0.1
4,077,958 - Rv3639c 0.13 -0.1
4,078,521 + -0.2
4,078,522 - -0.1
4,078,583 - -1.4
4,078,720 + Rv3640c 0.16 -0.2
4,078,720 + Rv3640c 0.16 -0.9
4,078,793 + Rv3640c 0.22 -0.5
4,079,245 - Rv3640c 0.59 -0.4
4,079,245 - Rv3640c 0.59 -1.4
4,079,245 - Rv3640c 0.59 -2.3
4,079,245 - Rv3640c 0.59 +0.6
4,079,259 + Rv3640c 0.60 -1.4
4,079,413 + Rv3640c 0.73 -0.4
4,079,414 - Rv3640c 0.73 -2.1
4,079,424 + Rv3640c 0.73 -1.1
4,079,812 - -0.7
4,079,867 + +0.3
4,079,917 + -0.9
4,079,917 + -0.2
4,079,917 + +0.0
4,079,935 + -1.1
4,080,136 + Rv3641c 0.33 -0.0
4,080,137 - Rv3641c 0.33 +0.1
4,080,137 - Rv3641c 0.33 -0.8
4,080,361 + Rv3641c 0.69 -0.1
4,080,511 + +2.0
4,080,512 - -0.5
4,080,512 - -0.6
4,080,584 + -0.4
4,080,584 + -0.8
4,080,585 - -2.4
4,080,638 + Rv3642c 0.34 +0.2
4,080,638 + Rv3642c 0.34 -0.4

Or see this region's nucleotide sequence