Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1720c

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1719 and GFF1787 are separated by 192 nucleotidesGFF1787 and Rv1720c are separated by 343 nucleotidesRv1720c and Rv1721c overlap by 4 nucleotidesRv1721c and Rv1722 are separated by 217 nucleotides Rv1719: Rv1719 - Probable transcriptional regulatory protein, at 1,945,641 to 1,946,420 Rv1719 GFF1787 - tRNA-Pro, at 1,946,613 to 1,946,686 GFF1787 Rv1720c: Rv1720c - Possible toxin VapC12, at 1,947,030 to 1,947,419 Rv1720c Rv1721c: Rv1721c - Possible antitoxin VapB12, at 1,947,416 to 1,947,643 Rv1721c Rv1722: Rv1722 - Possible carboxylase, at 1,947,861 to 1,949,345 Rv1722 Position (kb) 1947 1948Strain fitness (log2 ratio) -2 -1 0 1 2at 1946.502 kb on - strandat 1946.757 kb on + strandat 1946.758 kb on - strandat 1946.761 kb on + strandat 1946.761 kb on + strandat 1946.762 kb on - strandat 1947.056 kb on + strandat 1947.095 kb on + strand, within Rv1720cat 1947.096 kb on - strand, within Rv1720cat 1947.131 kb on - strand, within Rv1720cat 1947.131 kb on - strand, within Rv1720cat 1947.131 kb on - strand, within Rv1720cat 1947.150 kb on - strand, within Rv1720cat 1947.170 kb on - strand, within Rv1720cat 1947.960 kb on + strandat 1947.961 kb on - strandat 1947.999 kb on + strandat 1947.999 kb on + strandat 1947.999 kb on + strandat 1947.999 kb on + strandat 1948.000 kb on - strandat 1948.000 kb on - strandat 1948.032 kb on + strand, within Rv1722at 1948.032 kb on + strand, within Rv1722at 1948.033 kb on - strand, within Rv1722at 1948.033 kb on - strand, within Rv1722at 1948.036 kb on - strand, within Rv1722at 1948.036 kb on - strand, within Rv1722at 1948.036 kb on - strand, within Rv1722at 1948.036 kb on - strand, within Rv1722at 1948.362 kb on + strand, within Rv1722at 1948.362 kb on + strand, within Rv1722at 1948.363 kb on - strand, within Rv1722

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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1,946,502 - -1.1
1,946,757 + -0.3
1,946,758 - -1.0
1,946,761 + +1.6
1,946,761 + -0.0
1,946,762 - +2.6
1,947,056 + +1.6
1,947,095 + Rv1720c 0.17 -0.3
1,947,096 - Rv1720c 0.17 -1.5
1,947,131 - Rv1720c 0.26 -1.0
1,947,131 - Rv1720c 0.26 -1.3
1,947,131 - Rv1720c 0.26 +0.4
1,947,150 - Rv1720c 0.31 +0.3
1,947,170 - Rv1720c 0.36 -1.9
1,947,960 + +0.0
1,947,961 - -0.9
1,947,999 + +0.1
1,947,999 + +0.3
1,947,999 + +1.6
1,947,999 + +0.1
1,948,000 - +0.6
1,948,000 - -0.9
1,948,032 + Rv1722 0.12 +1.1
1,948,032 + Rv1722 0.12 +0.4
1,948,033 - Rv1722 0.12 -0.4
1,948,033 - Rv1722 0.12 -0.5
1,948,036 - Rv1722 0.12 -0.6
1,948,036 - Rv1722 0.12 -1.9
1,948,036 - Rv1722 0.12 +0.5
1,948,036 - Rv1722 0.12 +0.2
1,948,362 + Rv1722 0.34 +1.3
1,948,362 + Rv1722 0.34 +0.1
1,948,363 - Rv1722 0.34 +0.5

Or see this region's nucleotide sequence