Experiment: 7H9 with Sisomicin 0.07 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0456c and Rv0456A are separated by 272 nucleotides Rv0456A and Rv0456B overlap by 14 nucleotides Rv0456B and Rv0457c are separated by 68 nucleotides Rv0457c and Rv0458 are separated by 67 nucleotides
Rv0456c: Rv0456c - enoyl-CoA hydratase EchA2 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 545,889 to 546,803
Rv0456c
Rv0456A: Rv0456A - Possible toxin MazF1, at 547,076 to 547,357
Rv0456A
Rv0456B: Rv0456B - Possible antitoxin MazE1, at 547,344 to 547,517
Rv0456B
Rv0457c: Rv0457c - Probable peptidase, at 547,586 to 549,607
Rv0457c
Rv0458: Rv0458 - Probable aldehyde dehydrogenase, at 549,675 to 551,198
Rv0458
Position (kb) 547
548
549
550 Strain fitness (log2 ratio) -2
-1
0
1
2 at 546.601 kb on + strand, within Rv0456c at 546.772 kb on + strand at 546.772 kb on + strand at 546.772 kb on + strand at 546.773 kb on - strand at 546.803 kb on + strand at 546.804 kb on - strand at 547.036 kb on + strand at 547.036 kb on + strand at 547.036 kb on + strand at 547.037 kb on - strand at 547.245 kb on - strand, within Rv0456A at 547.360 kb on - strand at 547.474 kb on - strand, within Rv0456B at 547.481 kb on + strand, within Rv0456B at 547.481 kb on + strand, within Rv0456B at 547.482 kb on - strand, within Rv0456B at 547.482 kb on - strand, within Rv0456B at 547.482 kb on - strand, within Rv0456B at 547.482 kb on - strand, within Rv0456B at 547.484 kb on + strand, within Rv0456B at 547.491 kb on + strand, within Rv0456B at 547.492 kb on - strand, within Rv0456B at 547.494 kb on + strand, within Rv0456B at 547.497 kb on + strand, within Rv0456B at 547.497 kb on + strand, within Rv0456B at 547.505 kb on - strand at 547.507 kb on + strand at 547.515 kb on - strand at 547.690 kb on - strand at 547.787 kb on + strand at 547.787 kb on + strand at 547.879 kb on - strand, within Rv0457c at 548.178 kb on + strand, within Rv0457c at 548.179 kb on - strand, within Rv0457c at 548.179 kb on - strand, within Rv0457c at 548.224 kb on - strand, within Rv0457c at 548.313 kb on + strand, within Rv0457c at 548.357 kb on + strand, within Rv0457c at 548.530 kb on + strand, within Rv0457c at 548.634 kb on + strand, within Rv0457c at 548.635 kb on - strand, within Rv0457c at 548.859 kb on + strand, within Rv0457c at 549.223 kb on - strand, within Rv0457c at 549.330 kb on + strand, within Rv0457c at 549.330 kb on + strand, within Rv0457c at 549.331 kb on - strand, within Rv0457c at 549.394 kb on - strand, within Rv0457c at 549.394 kb on - strand, within Rv0457c at 549.399 kb on + strand, within Rv0457c at 549.420 kb on + strand at 549.567 kb on - strand at 549.570 kb on + strand at 549.720 kb on + strand at 550.272 kb on + strand, within Rv0458 at 550.273 kb on - strand, within Rv0458 at 550.273 kb on - strand, within Rv0458 at 550.428 kb on + strand, within Rv0458 at 550.429 kb on - strand, within Rv0458 at 550.429 kb on - strand, within Rv0458 at 550.488 kb on + strand, within Rv0458
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM remove 546,601 + Rv0456c 0.78 -1.0 546,772 + +1.1 546,772 + -0.7 546,772 + -1.5 546,773 - +0.7 546,803 + -0.6 546,804 - -0.0 547,036 + -0.3 547,036 + +0.8 547,036 + +0.2 547,037 - -2.4 547,245 - Rv0456A 0.60 -2.1 547,360 - -0.3 547,474 - Rv0456B 0.75 +0.5 547,481 + Rv0456B 0.79 -0.3 547,481 + Rv0456B 0.79 +0.4 547,482 - Rv0456B 0.79 +0.8 547,482 - Rv0456B 0.79 +0.3 547,482 - Rv0456B 0.79 -0.9 547,482 - Rv0456B 0.79 -0.7 547,484 + Rv0456B 0.80 +0.4 547,491 + Rv0456B 0.84 -0.2 547,492 - Rv0456B 0.85 -0.8 547,494 + Rv0456B 0.86 -1.1 547,497 + Rv0456B 0.88 +1.0 547,497 + Rv0456B 0.88 -0.2 547,505 - -2.2 547,507 + +1.7 547,515 - +0.7 547,690 - -1.3 547,787 + -0.8 547,787 + -0.2 547,879 - Rv0457c 0.14 +0.0 548,178 + Rv0457c 0.29 +0.2 548,179 - Rv0457c 0.29 +0.1 548,179 - Rv0457c 0.29 +1.0 548,224 - Rv0457c 0.32 -0.1 548,313 + Rv0457c 0.36 -1.1 548,357 + Rv0457c 0.38 -0.2 548,530 + Rv0457c 0.47 -0.5 548,634 + Rv0457c 0.52 +1.5 548,635 - Rv0457c 0.52 +1.7 548,859 + Rv0457c 0.63 +2.7 549,223 - Rv0457c 0.81 -0.2 549,330 + Rv0457c 0.86 +1.1 549,330 + Rv0457c 0.86 +0.4 549,331 - Rv0457c 0.86 -2.4 549,394 - Rv0457c 0.89 +1.2 549,394 - Rv0457c 0.89 +0.1 549,399 + Rv0457c 0.90 -1.7 549,420 + +0.1 549,567 - -0.4 549,570 + -0.3 549,720 + +0.5 550,272 + Rv0458 0.39 -0.2 550,273 - Rv0458 0.39 -0.3 550,273 - Rv0458 0.39 +0.7 550,428 + Rv0458 0.49 +0.2 550,429 - Rv0458 0.49 +0.0 550,429 - Rv0458 0.49 +0.4 550,488 + Rv0458 0.53 +0.5
Or see this region's nucleotide sequence