Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2850c

Experiment: 7H9 with Sisomicin 0.07 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2848c and Rv2849c overlap by 1 nucleotidesRv2849c and Rv2850c are separated by 20 nucleotidesRv2850c and Rv2851c overlap by 4 nucleotidesRv2851c and Rv2852c are separated by 58 nucleotides Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521 Rv2848c Rv2849c: Rv2849c - Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity), at 3,157,521 to 3,158,144 Rv2849c Rv2850c: Rv2850c - Possible magnesium chelatase, at 3,158,165 to 3,160,054 Rv2850c Rv2851c: Rv2851c - GCN5-related N-acetyltransferase, at 3,160,051 to 3,160,521 Rv2851c Rv2852c: Rv2852c - Probable malate:quinone oxidoreductase Mqo (malate dehydrogenase [acceptor]), at 3,160,580 to 3,162,061 Rv2852c Position (kb) 3158 3159 3160 3161Strain fitness (log2 ratio) -2 -1 0 1 2at 3157.312 kb on - strand, within Rv2848cat 3157.402 kb on + strandat 3157.721 kb on - strand, within Rv2849cat 3157.841 kb on + strand, within Rv2849cat 3157.842 kb on - strand, within Rv2849cat 3158.152 kb on + strandat 3158.153 kb on - strandat 3158.157 kb on - strandat 3159.665 kb on + strand, within Rv2850cat 3159.666 kb on - strand, within Rv2850cat 3160.154 kb on + strand, within Rv2851cat 3160.154 kb on + strand, within Rv2851cat 3160.169 kb on + strand, within Rv2851cat 3160.169 kb on + strand, within Rv2851cat 3160.267 kb on - strand, within Rv2851cat 3160.402 kb on + strand, within Rv2851cat 3160.522 kb on - strandat 3160.562 kb on + strandat 3160.563 kb on - strandat 3160.593 kb on - strandat 3160.795 kb on + strand, within Rv2852cat 3160.986 kb on + strand, within Rv2852c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
remove
3,157,312 - Rv2848c 0.85 +0.1
3,157,402 + -0.9
3,157,721 - Rv2849c 0.32 -0.3
3,157,841 + Rv2849c 0.51 +0.8
3,157,842 - Rv2849c 0.51 +0.1
3,158,152 + -1.0
3,158,153 - -0.6
3,158,157 - -1.8
3,159,665 + Rv2850c 0.79 +0.6
3,159,666 - Rv2850c 0.79 -1.3
3,160,154 + Rv2851c 0.22 +0.1
3,160,154 + Rv2851c 0.22 -0.9
3,160,169 + Rv2851c 0.25 -1.3
3,160,169 + Rv2851c 0.25 -0.8
3,160,267 - Rv2851c 0.46 -2.2
3,160,402 + Rv2851c 0.75 +0.4
3,160,522 - +0.9
3,160,562 + -0.9
3,160,563 - -0.2
3,160,593 - +0.0
3,160,795 + Rv2852c 0.15 -0.4
3,160,986 + Rv2852c 0.27 +2.6

Or see this region's nucleotide sequence