Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1063c

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1061 and Rv1062 are separated by 4 nucleotidesRv1062 and Rv1063c are separated by 0 nucleotidesRv1063c and Rv1064c are separated by 80 nucleotidesRv1064c and Rv1065 are separated by 111 nucleotides Rv1061: Rv1061 - Conserved protein, at 1,184,015 to 1,184,878 Rv1061 Rv1062: Rv1062 - Conserved hypothetical protein, at 1,184,883 to 1,185,740 Rv1062 Rv1063c: Rv1063c - Conserved hypothetical protein, at 1,185,741 to 1,186,823 Rv1063c Rv1064c: Rv1064c - Possible lipoprotein LpqV, at 1,186,904 to 1,187,323 Rv1064c Rv1065: Rv1065 - Conserved hypothetical protein, at 1,187,435 to 1,188,001 Rv1065 Position (kb) 1185 1186 1187Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1185.082 kb on - strand, within Rv1062at 1185.448 kb on - strand, within Rv1062at 1185.880 kb on - strand, within Rv1063cat 1185.905 kb on - strand, within Rv1063cat 1185.917 kb on + strand, within Rv1063cat 1185.917 kb on + strand, within Rv1063cat 1185.918 kb on - strand, within Rv1063cat 1186.122 kb on - strand, within Rv1063cat 1186.375 kb on - strand, within Rv1063cat 1186.444 kb on - strand, within Rv1063cat 1186.559 kb on + strand, within Rv1063cat 1186.559 kb on + strand, within Rv1063cat 1186.560 kb on - strand, within Rv1063cat 1186.696 kb on + strand, within Rv1063cat 1187.037 kb on + strand, within Rv1064cat 1187.109 kb on + strand, within Rv1064cat 1187.109 kb on + strand, within Rv1064cat 1187.112 kb on + strand, within Rv1064cat 1187.112 kb on + strand, within Rv1064cat 1187.113 kb on - strand, within Rv1064cat 1187.113 kb on - strand, within Rv1064cat 1187.307 kb on + strandat 1187.334 kb on + strandat 1187.334 kb on + strandat 1187.334 kb on + strandat 1187.335 kb on - strandat 1187.440 kb on + strandat 1187.441 kb on - strandat 1187.603 kb on + strand, within Rv1065at 1187.603 kb on + strand, within Rv1065at 1187.603 kb on + strand, within Rv1065at 1187.635 kb on + strand, within Rv1065at 1187.636 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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1,185,082 - Rv1062 0.23 +0.7
1,185,448 - Rv1062 0.66 +0.7
1,185,880 - Rv1063c 0.13 -1.3
1,185,905 - Rv1063c 0.15 -0.4
1,185,917 + Rv1063c 0.16 -0.9
1,185,917 + Rv1063c 0.16 +0.5
1,185,918 - Rv1063c 0.16 -1.5
1,186,122 - Rv1063c 0.35 -0.3
1,186,375 - Rv1063c 0.59 -1.0
1,186,444 - Rv1063c 0.65 -0.6
1,186,559 + Rv1063c 0.76 -1.3
1,186,559 + Rv1063c 0.76 -1.1
1,186,560 - Rv1063c 0.76 +3.0
1,186,696 + Rv1063c 0.88 -1.4
1,187,037 + Rv1064c 0.32 -1.8
1,187,109 + Rv1064c 0.49 +0.7
1,187,109 + Rv1064c 0.49 +0.4
1,187,112 + Rv1064c 0.50 -0.8
1,187,112 + Rv1064c 0.50 -1.3
1,187,113 - Rv1064c 0.50 -1.0
1,187,113 - Rv1064c 0.50 -0.9
1,187,307 + -1.8
1,187,334 + +0.5
1,187,334 + +0.7
1,187,334 + -0.5
1,187,335 - +0.8
1,187,440 + +0.5
1,187,441 - +2.4
1,187,603 + Rv1065 0.30 +3.0
1,187,603 + Rv1065 0.30 -2.0
1,187,603 + Rv1065 0.30 -0.1
1,187,635 + Rv1065 0.35 -0.6
1,187,636 - Rv1065 0.35 -0.4
1,187,648 - Rv1065 0.38 +1.9
1,187,648 - Rv1065 0.38 -1.7
1,187,648 - Rv1065 0.38 +0.2

Or see this region's nucleotide sequence