Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0208c

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0206c and Rv0207c are separated by 65 nucleotidesRv0207c and Rv0208c are separated by 2 nucleotidesRv0208c and Rv0209 are separated by 131 nucleotides Rv0206c: Rv0206c - Possible conserved transmembrane transport protein MmpL3, at 244,484 to 247,318 Rv0206c Rv0207c: Rv0207c - Conserved hypothetical protein, at 247,384 to 248,112 Rv0207c Rv0208c: Rv0208c - Hypothetical methlytransferase (methylase), at 248,115 to 248,906 Rv0208c Rv0209: Rv0209 - Hypothetical protein, at 249,038 to 250,123 Rv0209 Position (kb) 248 249Strain fitness (log2 ratio) -2 -1 0 1 2at 247.723 kb on + strand, within Rv0207cat 247.724 kb on - strand, within Rv0207cat 247.724 kb on - strand, within Rv0207cat 248.053 kb on + strandat 248.120 kb on + strandat 248.206 kb on + strand, within Rv0208cat 248.206 kb on + strand, within Rv0208cat 248.311 kb on + strand, within Rv0208cat 248.392 kb on - strand, within Rv0208cat 248.581 kb on + strand, within Rv0208cat 248.734 kb on - strand, within Rv0208cat 248.862 kb on + strandat 248.863 kb on - strandat 249.282 kb on - strand, within Rv0209at 249.436 kb on + strand, within Rv0209at 249.437 kb on - strand, within Rv0209at 249.437 kb on - strand, within Rv0209at 249.619 kb on - strand, within Rv0209

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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247,723 + Rv0207c 0.47 -1.3
247,724 - Rv0207c 0.47 +0.8
247,724 - Rv0207c 0.47 -1.0
248,053 + -0.7
248,120 + -2.5
248,206 + Rv0208c 0.11 +0.7
248,206 + Rv0208c 0.11 +0.2
248,311 + Rv0208c 0.25 -0.6
248,392 - Rv0208c 0.35 +1.5
248,581 + Rv0208c 0.59 -1.1
248,734 - Rv0208c 0.78 +1.9
248,862 + -1.2
248,863 - -0.9
249,282 - Rv0209 0.22 -0.7
249,436 + Rv0209 0.37 -0.2
249,437 - Rv0209 0.37 +0.4
249,437 - Rv0209 0.37 +1.5
249,619 - Rv0209 0.53 -1.6

Or see this region's nucleotide sequence