Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3522

Experiment: 7H9 with nitrate 4 mM

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrate 4 mM
3,957,509	+				+1.7
3,957,535	-				-1.2
3,957,620	+		Rv3521	0.11	-2.6
3,957,620	+		Rv3521	0.11	+0.5
3,957,621	-		Rv3521	0.11	-0.4
3,957,635	+		Rv3521	0.12	+0.3
3,957,635	+		Rv3521	0.12	-0.2
3,958,023	-		Rv3521	0.55	+1.2
3,958,023	-		Rv3521	0.55	-0.1
3,958,083	+		Rv3521	0.62	+2.9
3,958,086	-		Rv3521	0.62	+1.9
3,958,220	+		Rv3521	0.77	+0.9
3,958,221	-		Rv3521	0.77	+0.6
3,958,233	-		Rv3521	0.78	-0.9
3,958,373	+				+0.3
3,958,415	+				-1.6
3,958,415	+				-0.1
3,958,416	-				-0.2
3,958,430	+				+2.9
3,958,431	-				-0.0
3,958,516	+				+1.6
3,958,557	+		Rv3522	0.10	-1.3
3,958,557	+		Rv3522	0.10	-0.7
3,958,557	+		Rv3522	0.10	-0.7
3,958,725	-		Rv3522	0.26	+0.3
3,958,734	-		Rv3522	0.27	-0.0
3,958,734	-		Rv3522	0.27	-0.7
3,958,838	+		Rv3522	0.37	-0.1
3,958,884	+		Rv3522	0.41	+0.3
3,958,885	-		Rv3522	0.41	-0.7
3,959,226	+		Rv3522	0.73	-0.8
3,959,226	+		Rv3522	0.73	-1.5
3,959,416	+				-0.5
3,959,417	-				-1.0
3,959,728	+		Rv3523	0.17	-0.3
3,959,728	+		Rv3523	0.17	+1.0
3,959,728	+		Rv3523	0.17	+1.9
3,959,729	-		Rv3523	0.17	-0.7
3,959,812	+		Rv3523	0.24	+0.7
3,959,979	+		Rv3523	0.38	-0.3
3,959,979	+		Rv3523	0.38	-0.5
3,959,982	-		Rv3523	0.38	-0.7