Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1517

Experiment: 7H9 with nitrate 4 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1516c and Rv1517 are separated by 331 nucleotidesRv1517 and Rv1518 are separated by 8 nucleotides Rv1516c: Rv1516c - Probable sugar transferase, at 1,707,529 to 1,708,539 Rv1516c Rv1517: Rv1517 - Conserved hypothetical transmembrane protein, at 1,708,871 to 1,709,635 Rv1517 Rv1518: Rv1518 - Conserved hypothetical protein, at 1,709,644 to 1,710,603 Rv1518 Position (kb) 1708 1709 1710Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1708.217 kb on - strand, within Rv1516cat 1708.217 kb on - strand, within Rv1516cat 1708.238 kb on + strand, within Rv1516cat 1708.571 kb on + strandat 1708.571 kb on + strandat 1708.664 kb on - strandat 1708.665 kb on + strandat 1708.753 kb on + strandat 1708.855 kb on - strandat 1708.857 kb on + strandat 1708.858 kb on - strandat 1708.858 kb on - strandat 1709.064 kb on + strand, within Rv1517at 1709.064 kb on + strand, within Rv1517at 1709.064 kb on + strand, within Rv1517at 1709.064 kb on + strand, within Rv1517at 1709.065 kb on - strand, within Rv1517at 1709.065 kb on - strand, within Rv1517at 1709.065 kb on - strand, within Rv1517at 1709.300 kb on - strand, within Rv1517at 1709.495 kb on + strand, within Rv1517at 1709.550 kb on + strand, within Rv1517at 1709.612 kb on + strandat 1709.626 kb on + strandat 1709.698 kb on - strandat 1709.755 kb on - strand, within Rv1518at 1709.755 kb on - strand, within Rv1518at 1709.938 kb on - strand, within Rv1518at 1710.243 kb on + strand, within Rv1518at 1710.244 kb on - strand, within Rv1518at 1710.247 kb on + strand, within Rv1518

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrate 4 mM
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1,708,217 - Rv1516c 0.68 +0.0
1,708,217 - Rv1516c 0.68 +2.8
1,708,238 + Rv1516c 0.70 -0.4
1,708,571 + +0.0
1,708,571 + -0.1
1,708,664 - -1.7
1,708,665 + +0.1
1,708,753 + +0.2
1,708,855 - -0.1
1,708,857 + +0.5
1,708,858 - -0.3
1,708,858 - +0.9
1,709,064 + Rv1517 0.25 -0.2
1,709,064 + Rv1517 0.25 -1.5
1,709,064 + Rv1517 0.25 +0.0
1,709,064 + Rv1517 0.25 -0.4
1,709,065 - Rv1517 0.25 -0.4
1,709,065 - Rv1517 0.25 -0.3
1,709,065 - Rv1517 0.25 -2.4
1,709,300 - Rv1517 0.56 -0.7
1,709,495 + Rv1517 0.82 -0.8
1,709,550 + Rv1517 0.89 -2.4
1,709,612 + -0.4
1,709,626 + +0.2
1,709,698 - +0.6
1,709,755 - Rv1518 0.12 +0.8
1,709,755 - Rv1518 0.12 -0.1
1,709,938 - Rv1518 0.31 -0.2
1,710,243 + Rv1518 0.62 -0.2
1,710,244 - Rv1518 0.62 -0.2
1,710,247 + Rv1518 0.63 -2.5

Or see this region's nucleotide sequence